Trial reportThorax2023
Automatic oxygen titration versus constant oxygen flow rates during walking in COPD: a randomised controlled, double-blind, crossover trial.
Trial report in Thorax, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of an Auto-Regulating Oxygen System Compared to Constant-Flow Oxygen During Walking in Hypoxemic COPD Patients - a Randomized Controlled Trial
OXYWILD - Automated Oxygen Titration With O2matic During Walking in Patients With Fibrotic Interstitial Lung Diseases (F-ILD): A Randomized Study
Automatic Oxygen Titration Versus Constant Oxygen Flow Rates During Exercise Training in Hypoxemic People With Chronic Lung Disease - a Randomized, Double-blind, Controlled Cross-over Pilot Study
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Automatically titrating oxygen system versus constant flow oxygen system during exercise in patients with COPD: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Trial
- Automated Oxygen Delivery in Home Setting for Patients with COPD on Long-Term Oxygen Therapy - A Randomized Crossover Feasibility Trial.International journal of chronic obstructive pulmonary disease · 2025Trial
- High-intensity non-invasive ventilation during exercise-training versus without in people with very severe COPD and chronic hypercapnic respiratory failure: a randomised controlled trial.BMJ open respiratory research · 2023Trial
- Automated Oxygen Titration During CPAP and Noninvasive Ventilation in Healthy Subjects With Induced Hypoxemia.Respiratory care · 2023Trial
- Automatic oxygen titration during exercise in pulmonary rehabilitation: a pilot trial.ERJ open research · 2026Article
- ERS Congress 2025: highlights from the Respiratory Clinical Care and Physiology Assembly.ERJ open research · 2026Article
- ERS Congress 2025: highlights from the Allied Respiratory Professionals Assembly.ERJ open research · 2026Article
- Digital twins for chronic lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- 2023 Year in Review: Home Oxygen Therapy.Respiratory care · 2024Review
- Supplemental oxygen and noninvasive ventilation.European respiratory review : an official journal of the European Respiratory Society · 2023Article
- 2022 Brazilian Thoracic Association recommendations for long-term home oxygen therapy.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleIn patients with COPD, oxygen (O
methodsFifty participants completed this prospective randomised controlled, double-blind, crossover trial. Participants performed two endurance shuttle walk tests (ESWTs) with: (1) exercise titrated CFOS (ESWT
resultsParticipants (median (IQR): age 66 (59, 70) years, FEV
conclusionIn patients with hypoxaemia with severe COPD the use of ATOS leads to significant, clinically relevant improvements in walking endurance time, SpO TRIAL REGISTRATION NUMBER: NCT03803384.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.