ArticleThe journal of allergy and clinical immunology. In practice2022
Determining the Clinical Course of Asthma in Pregnancy.
Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Asthma Control During Pregnancy and Adverse Perinatal Outcomes: A Systematic Review.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Pooled it
- Effect of Nursing Intervention Supported by Mobile Health Applications on Asthma Control, Maternal and Neonatal Outcomes Among Pregnant Women with Asthma.Healthcare (Basel, Switzerland) · 2026Article
- Maternal asthma activity and offspring asthma: a linked-data population study in Australia and Sweden.BMJ open respiratory research · 2026Article
- Article
- Asthma Medication Adherence and Exacerbations in Pregnancy: Bridging the Gap Between Evidence and Practice.Allergy, asthma & immunology research · 2026Article
- The Developmental Origins of Asthma and COPD.Annual review of physiology · 2026Review
- Pregnancy, asthma and exacerbations: a population-based cohort.The European respiratory journal · 2025Article
- Interactions Between Prolactin, Intracellular Signaling, and Possible Implications in the Contractility and Pathophysiology of Asthma.International journal of molecular sciences · 2025Review
- Infant respiratory outcomes following asthma management and exacerbations in pregnancy.ERJ open research · 2025Article
- Asthma Exacerbation Risk in Pregnancy and Postpartum: Assessing the Impact of Gestational Diabetes Mellitus and Other Key Factors.The journal of allergy and clinical immunology. In practice · 2025Article
- Pregnancy does not affect progression of mild experimental asthma in sheep.The Journal of physiology · 2025Article
- Asthma and pregnancy.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Review
- Feasibility of remote spirometry monitoring of asthma in pregnancy.Respiratory medicine · 2024Article
- Breathing for Two: Asthma Management, Treatment, and Safety of Pharmacological Therapy during Pregnancy.Medicines (Basel, Switzerland) · 2024Review
- The Association of Periconception Asthma Medication Discontinuation with Adverse Obstetric Outcomes.American journal of perinatology · 2024Article
- Treatable Traits in Pregnant Women with Asthma.Respiration; international review of thoracic diseases · 2024Review
- Treatable traits in asthma during pregnancy: a call for a shift towards a precision-based management approach.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Maternal asthma in relation to infant size and body composition.The journal of allergy and clinical immunology. Global · 2023Article
- Challenges in the successful management of asthma during conception, pregnancy and delivery.Breathe (Sheffield, England) · 2022Review
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundAsthma is the most common chronic disease affecting pregnancy, and poor asthma control has been associated with adverse pregnancy outcomes. However, the trajectory of asthma control during pregnancy is not well understood or characterized.
objectiveTo identify and characterize trajectories of gestational asthma control in a US-based prospective pregnancy cohort.
methodsA k-means algorithm for joint longitudinal data was used to cluster pregnant women with and without asthma into gestational asthma control trajectories on the basis of daily activity limitation, nighttime symptoms, inhaler use, and respiratory symptoms.
resultsAmong 308 women with asthma, 2 trajectories of gestational asthma control were identified and labeled "same" (n = 184; 59.5%) or "worse" (n = 124; 40.5%). Contrary to previous studies, we did not observe women with better asthma control in pregnancy. Women belonging to the "worse" trajectory experienced frequent and stable activity limitation and inhaler use, as well as frequent and increasing nighttime symptoms (∼3 d/gestational week) and respiratory symptoms (∼5 times/wk). Women belonging to the "same" trajectory experienced infrequent and stable activity limitation, inhaler use, and respiratory symptoms, as well as infrequent and slightly increasing (∼1 d/gestational week) nighttime symptoms. Results from pregnant women without asthma (n = 107) suggest that pregnancy alone was not responsible for changes in symptoms over time.
conclusionsIn this US-based obstetric cohort receiving care according to standard clinical practice, gestational asthma control worsened for about 40% of women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.