Evidence map›Paper›PMID 34656782›Full record

ArticleJournal of shoulder and elbow surgery2022

Development of shoulder pain with job-related repetitive load: mechanisms of tendon pathology and anxiety.

Federico Pozzi, Catarina O Sousa, Hillary A Plummer, Brittany Andrade, Daniel Awokuse, Naoko Kono, Wendy J Mack, Shawn C Roll, Lori A Michener

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of shoulder and elbow surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02587897 (Sonographic Tissue Morphology in Early Stage Work-related Median Nerve Pathology), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02587897 completednot on this map

Sonographic Tissue Morphology in Early Stage Work-related Median Nerve Pathology

TypeobservationalSponsorUniversity of Southern CaliforniaRan2016 to 2023Enrolled176ConditionsCarpal Tunnel SyndromeArmsAcademic Coursework, Work-Related Hand Activities
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Federico PozziDepartment of Physical Therapy, University of Florida, Gainesville, FL, USA. Electronic address: fpozzi@phhp.ufl.edu.
Catarina O SousaDepartemento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Brazil.
Hillary A PlummerDivision of Biokinesiology, University of Southern California, Los Angeles, CA, USA.
Brittany AndradeDivision of Biokinesiology, University of Southern California, Los Angeles, CA, USA.
Daniel AwokuseDivision of Biokinesiology, University of Southern California, Los Angeles, CA, USA.
Naoko KonoDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Wendy J MackDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Shawn C RollUSC Chan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.
Lori A MichenerDivision of Biokinesiology, University of Southern California, Los Angeles, CA, USA.
University of Southern California · USUniversidade Federal do Rio Grande do Norte · BRUniversity of Florida · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Rehabilitation Research Career Development ProgramK12HD055929 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BROWN, DAVID A · 2007 to 2021
$11.7M
Sonographic tissue morphology in early stage work-related median nerve pathologyR01OH010665 · OH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROLL, SHAWN C. · 2015 to 2018
$2.3M
ACL HHS R01OH010665NCATS NIH HHS UL1 TR001855NICHD NIH HHS K12 HD055929NIOSH CDC HHS R01 OH010665
6 · The paper itself

Abstract

backgroundThe paucity of longitudinal clinical studies limits our understanding of the development of shoulder pain with repetitive shoulder tasks, and its association with underlying mind and body mechanisms. Tendon thickening characterizes painful shoulder supraspinatus tendinopathy, and the perception of pain can be affected by the presence of psychological factors such as anxiety and depression. This study determined the incidence of shoulder pain in novice individuals exposed to repetitive shoulder tasks, and the associated change in outcomes of supraspinatus tendon morphology and measures of anxiety and depression.

methodsWe recruited dental hygiene (DH) students (n = 45, novice and exposed to shoulder repetitive tasks) and occupational therapy (OT) students (n = 52, novice, but not exposed to shoulder repetitive tasks), following them over their first year of training. We measured shoulder pain, supraspinatus morphology via ultrasonography, and psychosocial distress via the Hospital Anxiety and Depression Scale. We compared the incidence of shoulder pain (defined as a change of visual analog scale for pain score greater than the minimal clinically important difference) between DH and OT students using Fisher exact test. We used mixed effects models to longitudinally compare the change in outcomes between 3 groups: DH students who develop and did not develop shoulder pain, and OT students.

resultsThe incidence of shoulder pain is higher in DH students (relative risk = 4.0, 95% confidence interval [CI] 1.4, 11.4). After 1 year, DH students with pain had the greatest thickening of the supraspinatus (0.7 mm, 95% CI 0.4, 0.9). The change in supraspinatus thickness of DH students with pain was greater than both DH students with no pain (0.4 mm, 95% CI 0.1, 0.8) and OT students (0.9 mm, 95% CI 0.5, 1.2). Anxiety score increased 3.8 points (95% CI 1.6, 5.1) in DH students with pain, and 43% of DH students with pain had abnormal anxiety score at 1 year (relative risk = 2.9, 95% CI 1.0, 8.6).

conclusionOur results provide support for the theoretical model of repetitive load as a mechanism of tendinopathy. The supraspinatus tendon thickens in the presence of repetitive tasks, and it thickens the most in those who develop shoulder pain. Concurrently, anxiety develops with shoulder pain, indicating a potential maladaptive central mechanism that may impact the perception of pain.

Indexed as

Rotator Cuff InjuriesShoulder PainAnxietyHumansRotator CuffTendonsUltrasonographyanxietypainshoulderSupraspinatustendinopathy

Identifiers

PMID34656782
PMCPMC9121627
OpenAlexW3205079427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.