Evidence map›Paper›PMID 34656182›Full record

ArticleLaboratory animal research2021

Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study.

Doo-Wan Cho, Hyoung-Yun Han, Mi-Jin Yang, Dong Ho Woo, Su-Cheol Han, Young-Su Yang

Open access · diamondAbstract read
In one paragraph

Article in Laboratory animal research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Doo-Wan Cho *Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Hyoung-Yun Han *Molecular Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Mi-Jin YangJeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Dong Ho WooPharmacology & Drug Abuse Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Su-Cheol HanJeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Young-Su YangJeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea. ysyang@kitox.re.kr.ORCID http://orcid.org/0000-0002-6633-8958
Korea Institute of Toxicology · KR

Funding

Korea Institute of Toxicology KK-2101Korea Institute of Toxicology KK-2107
6 · The paper itself

Abstract

backgroundTelemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device, the animals are either used for other studies or euthanatized. CASE PRESENTATION: Herein, we report the case of a living cynomolgus monkey (Macaca fascicularis) that was used for the entire experimental period, instead of euthanasia, after surgical removal of an implanted telemetry system. Radiography was used to determine the status of the implanted telemetry, following which, a repair surgery was performed for removing the system; clinical signs were used to preserve the life of the cynomolgus monkey. Postoperative clinical signs, food consumption, hematology, and serum biochemistry were examined during the 12-month observational period. No abnormal readings or conditions were observed in the subject after implant removal.

conclusionsThis study may be a useful case report for living cynomolgus monkeys in telemetry implantations used throughout the study period. We suggest minimizing the suffering and improving the welfare of these animals.

Indexed as

Cynomolgus monkeyImplantationSurgeryTelemetryWelfare

Identifiers

PMID34656182
PMCPMC8520245
OpenAlexW3205411390

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.