Evidence map›Paper›PMID 34655973›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2021

Racial and Ethnic Disparities in Functional Outcome after Thrombectomy: A Cohort Study of an Integrated Stroke Network.

Erica Jones, Aditya Kumar, Victor Lopez-Rivera, Jacob Sebaugh, Haris Kamal, Sunil A Sheth, Anjail Sharrief, Alicia Zha

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Erica JonesDepartment of Neurology, University of Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390, United States. Electronic address: Erica.Jones2@UTSouthwestern.edu.
Aditya KumarDepartment of Neurology, University of Texas McGovern Medical School, Houston, TX 77030, United States.
Victor Lopez-RiveraDepartment of Neurology, University of Texas McGovern Medical School, Houston, TX 77030, United States.
Jacob SebaughDepartment of Neurology, University of Texas McGovern Medical School, Houston, TX 77030, United States.
Haris KamalDepartment of Neurosurgery, New York Medical College Westchester Medical Center, White Plains, NY 10605, United States.
Sunil A ShethDepartment of Neurology, University of Texas McGovern Medical School, Houston, TX 77030, United States.
Anjail SharriefDepartment of Neurology, University of Texas McGovern Medical School, Houston, TX 77030, United States; Department of Neurology, Institute of Stroke and Cerebrovascular Disease, University of Texas McGovern Medical School, Houston, TX 77030, United States.
Alicia ZhaDepartment of Neurology, University of Texas McGovern Medical School, Houston, TX 77030, United States; Department of Neurology, Institute of Stroke and Cerebrovascular Disease, University of Texas McGovern Medical School, Houston, TX 77030, United States.
The University of Texas Health Science Center · USSouthwestern Medical Center · USWestchester Medical Center · US

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
THE UNIVERSITY OF TEXAS HOUSTON STROKE TRAINING PROGRAMT32NS007412 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SAVITZ, SEAN I · 1998 to 2023
$4.6M
NCATS NIH HHS UL1 TR003167NINDS NIH HHS T32 NS007412
6 · The paper itself

Abstract

objectivesPrevious studies have shown racial disparities in access to treatment and outcomes in ischemic stroke patients. We sought to define racial disparities in functional outcomes among ischemic stroke patients receiving endovascular thrombectomy (EVT). MATERIALS AND

methodsWe performed a retrospective review of patients in our institution's prospectively collected stroke patient registry from 08/2015 to 06/2019 at 1 comprehensive and 2 thrombectomy-ready stroke centers. We reviewed patients aged ≥ 18 who received mechanical thrombectomy including only patients with race/ethnicity data belonging to the 3 largest race/ethnic groups: Non-Hispanic White (NHW), Non-Hispanic Black (NHB), and Hispanic (HIS). We compared baseline characteristics and performed multivariable logistic regression to evaluate differences in good functional outcome defined as 90-day modified Rankin score (90 day mRS 0-2) as the primary outcome. Secondary outcomes were discharge disposition, length of stay, and excellent functional outcome (90 day mRS 0-1). Results are given as OR [95% CI].

resultsAmong 666 patients that met inclusion criteria, 45% were NHW, 30% were NHB, and 19% were HIS. NHB and HIS patients were younger than NHW (average age NHB 62; HIS 64; and NHW 70; p < 0.001). Diabetes was more prevalent in NHB (32%, p = 0.02) and HIS (47%, p < 0.001) compared to NHW (23%). There were no significant racial differences in pre-morbid mRS, arrival NIHSS, tPA treatment rates. There was no difference in primary outcome by race comparing NHW to the other racial groups (OR 1.08 [0.68-1.72]) but compared to HIS patients, NHW had a higher likelihood of the secondary outcome of excellent functional outcome (aOR 2.23 [1.01-4.93]) defined as mRS 0-1.

conclusionsIn this study of over 600 patients treated with EVT, we did not find significant racial disparities in functional outcome except for less excellent functional outcome in HIS compared to NHW. Further study on disparities in post-acute stroke care is needed.

Indexed as

EthnicityHealth Status DisparitiesIschemic StrokeRacial GroupsThrombectomyAgedBlack or African AmericanHispanic or LatinoHumansMiddle AgedRetrospective StudiesTreatment OutcomeWhite PeopleDisparitiesOutcomesRacialThrombectomy

Identifiers

PMID34655973
PMCPMC8578430
OpenAlexW3206862311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.