Evidence map›Paper›PMID 34655683›Full record

ArticleJournal of vascular surgery2022

Role of volume in small abdominal aortic aneurysm surveillance.

Sydney L Olson, Annalise M Panthofer, William Blackwelder, Michael L Terrin, John A Curci, B Timothy Baxter, Fred A Weaver, Jon S Matsumura, Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial Investigators

Open access · greenAbstract read
In one paragraph

Article in Journal of vascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Sydney L OlsonDivision of Vascular Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisc. Electronic address: olsons@surgery.wisc.edu.
Annalise M PanthoferDivision of Vascular Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisc.
William BlackwelderDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Md.
Michael L TerrinDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Md.
John A CurciDivision of Vascular Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
B Timothy BaxterDivision of Vascular Surgery, University of Nebraska School of Medicine, Omaha, Neb.
Fred A WeaverDivision of Vascular Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Calif.
Jon S MatsumuraDivision of Vascular Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisc.
Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial Investigators
University of Wisconsin–Madison · USUniversity of Maryland, Baltimore · USUniversity of Nebraska at Omaha · USUniversity of Southern California · USVanderbilt University Medical Center · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA^3CT )R01AG037120 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI BAXTER, BERNARD TIMOTHY, CURCI, JOHN A · 2011 to 2017
$12.2M
RESEARCH TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000262 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ANN L GRUBER-BALDINI, DENISE L ORWIG · 1998 to 2026
$8.2M
Doxycycline Treatment of Abdominal Aortic Aneurysm: PlanningR34AG028684 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI TERRIN, MICHAEL L. · 2007 to 2007
$101k
NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG037120NIA NIH HHS R34 AG028684NIA NIH HHS T32 AG000262
6 · The paper itself

Abstract

objectiveCurrent management of small abdominal aortic aneurysms (AAAs) primarily involves serial imaging surveillance of maximum transverse diameter (MTD) to estimate rupture risk. Other measurements, such as volume and tortuosity, are less well-studied and may help characterize and predict AAA progression. This study evaluated predictors of AAA volume growth and discusses the role of volume in clinical practice.

methodsSubjects from the Non-invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (baseline AAA MTD, 3.5-5.0 cm) with ≥2 computed tomography scans were included in this study (n = 250). Computed tomography scans were conducted approximately every 6 months over 2 years. MTD, volume, and tortuosity were used to model growth. Univariable and multivariable backwards elimination least squares regressions assessed associations with volume growth.

resultsBaseline MTD accounted for 43% of baseline volume variance (P < .0001). Mean volume growth rate was 10.4 cm

conclusionsBaseline AAA volume and MTD were found to be moderately correlated. On average, AAA volume grows about 10% annually. Baseline volume, tortuosity, MTD, current tobacco use, angiotensin II receptor blocker use, and history of diabetes mellitus were predictive of volume growth over time.

Indexed as

Aortic Aneurysm, AbdominalAngiotensin Receptor AntagonistsFemaleHumansMaleTomography, X-Ray ComputedAngiotensin Receptor AntagonistsAbdominal aortic aneurysmAneurysm growthAneurysm volumeCT surveillance

Identifiers

PMID34655683
PMCPMC8940629
OpenAlexW3195047444

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.