Evidence map›Paper›PMID 34655247›Full record

SynthesisJournal of medical virology2022

Covid-19 sequelae in working age patients: A systematic review.

Gabriele d'Ettorre, Elio Gentilini Cacciola, Letizia Santinelli, Gabriella De Girolamo, Ornella Spagnolello, Alessandro Russo, Lorenzo Tarsitani, Massimo Ciccozzi, Claudio M Mastroianni, Gabriella d'Ettorre and 1 more

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  12. Nurses' Experiences of Care in Portuguese Nursing Homes during the COVID-19 Pandemic: A Focus Group Study.International journal of environmental research and public health · 2023
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  14. Observational
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  16. Article
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  19. Long-Term Effects of COVID-19 on Workers in Health and Social Services in Germany.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Gabriele d'EttorreUnit of Occupational Prevention and Protection, ASL Lecce, Lecce, Italy.ORCID 0000-0001-8714-1612
Elio Gentilini CacciolaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Letizia SantinelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-5621-058X
Gabriella De GirolamoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-2667-0603
Ornella SpagnolelloDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-6201-389X
Alessandro RussoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-3846-4620
Lorenzo TarsitaniAzienda Ospedaliero, Universitaria Policlinico Umberto I, Rome, Italy.ORCID 0000-0002-1752-966X
Massimo CiccozziMedical Statistic and Molecular Epidemiology Unit, University of Biomedical Campus, Rome, Italy.ORCID 0000-0003-3866-9239
Claudio M MastroianniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-1286-467X
Gabriella d'EttorreDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-3571-5677
Giancarlo CeccarelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-5921-3180
Policlinico Umberto I · ITSapienza University of Rome · ITIstituto Nazionale di Statistica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the SARS-CoV-2 pandemic not yet being under control, post-Covid-19 syndrome is already a challenging topic: long-term multiorgan sequelae, although increasingly described, have not yet been systematized. As post-Covid-19 syndrome can significantly impact both the working capacity and the relationship life of surviving patients, we performed a systematic review of the evidence published over the last year and currently available in medical literature search databases (MEDLINE/Pubmed) and searching clinical trial registries, to evaluate the available evidence among workers. From 31 publications that initially matched inclusion criteria, 13 studies have been considered suitable for relevance and age of subjects. A wide range of patients (16%-87%) have post-Covid syndrome; pneumological and neuropsychological symptoms were the most common disorders reported. The most frequent organic sequel found in post-Covid patients was pulmonary fibrosis. The number of symptoms during acute SARS-CoV-2 infection, severity of the disease, and high serum levels of d-dimer were related to high risk of post-Covid syndrome. In conclusion, post-Covid-19 syndrome can significantly impact the health conditions of surviving patients. Rehabilitation and follow-up in multidisciplinary rehabilitation programs should be considered for working-age patients.

Indexed as

COVID-19Pulmonary FibrosisHumansPandemicsPost-Acute COVID-19 SyndromeSARS-CoV-2Covid-19neuropsychological symptomspneumological symptomspost-Covid syndromeSARS-CoVsequelaesystematic reviewworking age patients

Identifiers

PMID34655247
PMCPMC8661973
OpenAlexW3207814015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.