ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2022
Social Networks and Cognitive Reserve: Network Structure Moderates the Association Between Amygdalar Volume and Cognitive Outcomes.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A meta-analytical umbrella review assessing urban environment exposures and cognitive health outcomes.Age and ageing · 2026Pooled it
- Selected social and lifestyle correlates of brain health markers: the Cross-Cohort Collaboration Consortium.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- "Kinlessness", friend and family support, and cognitive function by region and urbanicity in the United States.Health & place · 2026Article
- The association between lifetime marital histories and later-life cognitive function: evidence from the United States and China.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Mid-to-late-life social network size and resilience to neurodegeneration: The Framingham Heart Study.BMC neurology · 2026Article
- Association between visceral adiposity index and incident dementia: a community-based cohort study.BMC psychiatry · 2026Article
- Social network structure and composition predicting cognitive impairment: racial/ethnic differences among older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Beyond the Block: Social Network Extralocality and Cognitive Function Among U.S. Older Adults.Journal of aging and health · 2026Article
- Cognitive Functioning in Rural Older Adults: The Mediating Role of Perceived Social Support.Healthcare (Basel, Switzerland) · 2026Article
- Social alienation and cognitive function among older adults: the mediating roles of ruminative thinking and self-neglect.Frontiers in public health · 2026Article
- Is social connection the key to prevention? Educational attainment, incident dementia, and the role of later-life social engagement.Innovation in aging · 2026Article
- The association between sports social capital and cognitive health: A longitudinal study of middle-aged and elderly adults in China.SSM - population health · 2025Article
- Life Course Associations of Sibling Relationships and Cognitive Functioning in Late Adulthood.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Factors Affecting Resilience and Prevention of Alzheimer's Disease and Related Dementias.Annals of neurology · 2024Review
- The Interplay of Race, Ethnicity, and Language in Caregiver Health: Insights from the National Social Life, Health, and Aging Project.Research square · 2024Article
- Article
- Shifting From Active to Passive Monitoring of Alzheimer Disease: The State of the Research.Journal of the American Heart Association · 2024Review
- Salience Network Functional Connectivity Mediates Association Between Social Engagement and Cognition in Non-Demented Older Adults: Exploratory Investigation.Journal of Alzheimer's disease reports · 2024Article
- Effect of Internet Use on Cognitive Function of Middle-Aged and Elderly Adults in China: Evidence from China Family Panel Studies.Journal of Alzheimer's disease reports · 2024Article
- Understanding factors associated with the trajectory of subjective cognitive complaints in groups with similar objective cognitive trajectories.Alzheimer's research & therapy · 2023Article
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Authors and funding
6 authors.
Funding
Abstract
objectivesThe cognitive reserve hypothesis has been proposed as a key mechanism explaining the link between social networks and cognitive function but has rarely been empirically tested using neuroimaging data. This study examines whether social network attributes moderate the association between amygdalar volume and cognitive function.
methodsData were from the Social Networks in Alzheimer Disease study (N = 154) and Indiana Alzheimer's Disease Research Center. Social networks were measured using the PhenX Social Network Battery. Regional data from magnetic resonance imaging (amygdalar volume [AV]) were analyzed using FreeSurfer software. Cognitive function was measured using the Montreal Cognitive Assessment (MoCA) and consensus diagnosis. Linear regression analyses were conducted to test the moderating role of social networks on the association between AV and cognitive function.
resultsParticipants with greater ability to span multiple social roles and subgroups within their networks scored higher on the MoCA after adjusting for sociodemographic variables, depression, frequency of contact, and AV. Social networks moderated the association between AV and cognitive function. DISCUSSION: Among participants who engaged in diverse and loosely connected social networks, the expected adverse cognitive effects of brain volume in regions implicated in socioemotional processing were attenuated. These findings suggest that cognitive stimulation achieved through social interaction with a diverse array of social relationships across multiple contexts may help promote cognitive reserve.
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