SynthesisThe European journal of neuroscience2021
Decision making in Parkinson's disease: An analysis of the studies using the Iowa Gambling Task.
Synthesis in The European journal of neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Creative thinking in Parkinson's disease: A systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Cognitive correlates of decision-making in Parkinson's disease: a systematic review.Frontiers in aging neuroscience · 2026Pooled it
- Decision making in Parkinson's disease: An analysis of the studies using the Iowa Gambling Task.The European journal of neuroscience · 2021Pooled it
- Dopamine modulation of motor and implicit learning contributions to auditory temporal attention.iScience · 2026Article
- From Inner Sense to Outer Action: Interoception and Impulsive Compulsive Behavior Disorders in Parkinson's Disease.Movement disorders clinical practice · 2025Article
- Reward circuit local field potential modulations precede risk taking.Brain : a journal of neurology · 2025Article
- Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment.NPJ Parkinson's disease · 2025Article
- Eye movements during the Iowa Gambling Task in Parkinson's disease: a brief report.Frontiers in psychology · 2025Article
- Sleep-Related Disorders in Parkinson's Disease: Mechanisms, Diagnosis, and Therapeutic Approaches.CNS & neurological disorders drug targets · 2025Review
- Brain Stimulation Techniques in Research and Clinical Practice: A Comprehensive Review of Applications and Therapeutic Potential in Parkinson's Disease.Brain sciences · 2024Review
- Deepening the decisional processes under value-based conditions in patients affected by Parkinson's disease: A comparative study.Cognitive, affective & behavioral neuroscience · 2024Article
- Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson's Disease.International journal of molecular sciences · 2024Article
- The effect of transcranial Direct Current Stimulation on the Iowa Gambling Task: a scoping review.Frontiers in psychology · 2024Article
- Decision-making under ambiguity and risk and executive functions in Parkinson's disease patients: A scoping review of the studies investigating the Iowa Gambling Task and the Game of Dice.Cognitive, affective & behavioral neuroscience · 2023Article
- Gambling associated risk-taking decision in cerebellar ataxia.Parkinsonism & related disorders · 2023Article
- Decision-making deficits in obsessive-compulsive disorder are associated with abnormality of recency and response consistency parameter in prospect valence learning model.Frontiers in psychiatry · 2023Article
- Aging-related changes in reward-based decision-making depend on punishment frequency: An fMRI study.Frontiers in aging neuroscience · 2023Article
- Executive Functions in Decision Making under Ambiguity and Risk in Healthy Adults: A Scoping Review Adopting the Hot and Cold Executive Functions Perspective.Brain sciences · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Parkinson's disease (PD) impairments in decision making can occur, in particular because of the tendency toward risky and rewarding options. The Iowa Gambling Task has been widely used to investigate decision processes involving these options. The task assesses the ability to manage risk and to learn from feedback. The present paper aims at critically examining those studies in which this task has been administered to PD patients, in order to understand possible anomalies in patients' decision processes and which variables are responsible for that. A meta-analysis has been conducted as well. Features of the task, sociodemographic and clinical aspects (including daily drugs intake), cognitive conditions and emotional disorders of the patients have been taken into account. Neural correlates of decision-making competences were considered. It emerged that PD patients show a trend of preference toward risky choices, probably due to an impairment in anticipating the unrewarding consequences or to an insensitiveness to punishment. The possible role played by dopamine medications in decision making under uncertain conditions, affecting basal ganglia and structures involved in the limbic loop, was discussed. Attention has been focused on some aspects that need to be investigated in further research, in order to delve into this issue and promote patients' quality of life.
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Registered trials
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