SynthesisThe Lancet. Digital health2021
Blockchain applications in health care for COVID-19 and beyond: a systematic review.
Synthesis in The Lancet. Digital health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The intelligent neonatal healthcare: a systematic review of machine learning architectures integrating the internet of medical things and blockchain.Frontiers in artificial intelligence · 2026Pooled it
- Literature review: Current trends and future prospects of digital vaccine supply chain support technology.Human vaccines & immunotherapeutics · 2025Pooled it
- Blockchain for Digital Health Governance: Evidence Gap Map and Scoping Review.Journal of medical Internet research · 2026Article
- Blockchain and digital twin integration for predictive and secure pandemic alerting.Scientific reports · 2025Article
- Strategizing data compliance in intelligent healthcare: A four-step solution.Chinese medical journal · 2025Article
- Blockchain in Health Care, Evolutionary or Revolutionary - An Evidence-Based Review.Journal of pharmacy & bioallied sciences · 2025Review
- Digital solutions for migrant and refugee health: a framework for analysis and action.The Lancet regional health. Europe · 2025Review
- Blockchain Technology in Digital Health and Medical Technologies.Blockchain in healthcare today · 2025Article
- Use of Blockchain Technology to Accelerate Digital Health Transformation Programs.Blockchain in healthcare today · 2025Review
- Efficient Use of Biological Data in the Web 3.0 Era by Applying Nonfungible Token Technology.Journal of medical Internet research · 2024Article
- [Blockchain in health: Transforming security and clinical data management].Atencion primaria · 2024Article
- Blockchain: What is the use case for physicians in 2024? A rapid review of the literature.Future healthcare journal · 2024Review
- Reflections about Blockchain in Health Data Sharing: Navigating a Disruptive Technology.International journal of environmental research and public health · 2024Article
- Blockchain Revolutionizing in Emergency Medicine: A Scoping Review of Patient Journey through the ED.Healthcare (Basel, Switzerland) · 2023Article
- A Comprehensive Survey on Pandemic Patient Monitoring System: Enabling Technologies, Opportunities, and Research Challenges.Wireless personal communications · 2023Review
- Effectiveness of the Internet of Things for Improving Working-Aged Women's Health in High-Income Countries: Protocol for a Systematic Review and Network Meta-analysis.JMIR research protocols · 2023Article
- Technology Roadmap for Flexible Sensors.ACS nano · 2023Review
- Non-fungible tokens for the management of health data.Nature medicine · 2023Article
- Vaccine supply chain management: An intelligent system utilizing blockchain, IoT and machine learning.Journal of business research · 2023Article
- Telemedicine for diabetes management during COVID-19: what we have learnt, what and how to implement.Frontiers in endocrinology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic has had a substantial and global impact on health care, and has greatly accelerated the adoption of digital technology. One of these emerging digital technologies, blockchain, has unique characteristics (eg, immutability, decentralisation, and transparency) that can be useful in multiple domains (eg, management of electronic medical records and access rights, and mobile health). We conducted a systematic review of COVID-19-related and non-COVID-19-related applications of blockchain in health care. We identified relevant reports published in MEDLINE, SpringerLink, Institute of Electrical and Electronics Engineers Xplore, ScienceDirect, arXiv, and Google Scholar up to July 29, 2021. Articles that included both clinical and technical designs, with or without prototype development, were included. A total of 85 375 articles were evaluated, with 415 full length reports (37 related to COVID-19 and 378 not related to COVID-19) eventually included in the final analysis. The main COVID-19-related applications reported were pandemic control and surveillance, immunity or vaccine passport monitoring, and contact tracing. The top three non-COVID-19-related applications were management of electronic medical records, internet of things (eg, remote monitoring or mobile health), and supply chain monitoring. Most reports detailed technical performance of the blockchain prototype platforms (277 [66·7%] of 415), whereas nine (2·2%) studies showed real-world clinical application and adoption. The remaining studies (129 [31·1%] of 415) were themselves of a technical design only. The most common platforms used were Ethereum and Hyperledger. Blockchain technology has numerous potential COVID-19-related and non-COVID-19-related applications in health care. However, much of the current research remains at the technical stage, with few providing actual clinical applications, highlighting the need to translate foundational blockchain technology into clinical use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.