Trial reportVaccine2021
A self-administered virtual reality intervention increases COVID-19 vaccination intention.
Trial report in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Communication-based interventions to increase COVID-19 vaccine willingness and uptake: a systematic review with meta-analysis.BMJ open · 2025Pooled it
- An effective COVID-19 vaccine hesitancy intervention focused on the relative risks of vaccination and infection.Scientific reports · 2024Trial
- Virtual reality reduces COVID-19 vaccine hesitancy in the wild: a randomized trial.Scientific reports · 2022Trial
- [Digital innovations in vaccination communication].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Article
- Using a Virtual Reality Tool to Provide Primary Prevention Training in the Construction Field Following a Periodic Medical Visit: Cross-Sectional Study.JMIR serious games · 2024Article
- Effect of information provision on parental intention toward COVID-19 vaccination for children: a nationwide survey experiment.Scientific reports · 2024Article
- Digital Gamification Tools to Enhance Vaccine Uptake: Scoping Review.JMIR serious games · 2024Article
- Article
- Promoting HPV Vaccination in People with HIV: Factors to Consider.International journal of environmental research and public health · 2023Article
- Experiencing herd immunity in virtual reality increases COVID-19 vaccination intention: Evidence from a large-scale field intervention study.Computers in human behavior · 2023Article
- The Evaluation of Web-Based Communication Interventions to Support Decisions About COVID-19 Vaccination Among Patients With Underlying Medical Conditions: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2023Article
- Public interest in the digital transformation accelerated by the COVID-19 pandemic and perception of its future impact.The Korean journal of internal medicine · 2022Article
- Impact of a Virtual Reality Curriculum on Human Papillomavirus Vaccination: A Pilot Trial.American journal of preventive medicine · 2022Article
- Virtual Reality Applications in Medicine During the COVID-19 Pandemic: Systematic Review.JMIR serious games · 2022Review
- Can extended reality in the metaverse revolutionise health communication?NPJ digital medicine · 2022Article
- Repeated information of benefits reduces COVID-19 vaccination hesitancy: Experimental evidence from Germany.PloS one · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective interventions for increasing people's intention to get vaccinated are crucial for global health, especially considering COVID-19. We devised a novel intervention using virtual reality (VR) consisting of a consultation with a general practitioner for communicating the benefits of COVID-19 vaccination and, in turn, increasing the intention to get vaccinated against COVID-19. We conducted a preregistered online experiment with a 2×2 between-participant design. People with eligible VR headsets were invited to install our experimental application and complete the ten minute virtual consultation study at their own discretion. Participants were randomly assigned across two age conditions (young or old self-body) and two communication conditions (with provision of personal benefit of vaccination only, or collective and personal benefit). The primary outcome was vaccination intention (score range 1-100) measured three times: immediately before and after the study, as well as one week later. Five-hundred-and-seven adults not vaccinated against COVID-19 were recruited. Among the 282 participants with imperfect vaccination intentions (<100), the VR intervention increased pre-to-post vaccination intentions across intervention conditions (mean difference 8.6, 95% CI 6.1 to 11.1,p<0.0001). The pre-to-post difference significantly correlated with the vaccination intention one week later, ρ=0.20,p<0.0001. The VR intervention was effective in increasing COVID-19 vaccination intentions both when only personal benefits and personal and collective benefits of vaccination were communicated, with significant retention one week after the intervention. Utilizing recent evidence from health psychology and embodiment research to develop immersive environments with customized and salient communication efforts could therefore be an effective tool to complement public health campaigns.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.