Evidence map›Paper›PMID 34654429›Full record

ArticleBMC health services research2021

An economic evaluation of an intervention to increase demand for medical male circumcision among men aged 25-49 years in South Africa.

M Holmes, R Mukora, D Mudzengi, S Charalambous, C M Chetty-Makkan, H Kisbey-Green, M Maraisane, J Grund

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

M HolmesCenters for Disease Control and Prevention, Atlanta, GA, USA. mholmes@spelman.edu.ORCID http://orcid.org/0000-0003-1247-0141
R MukoraThe Aurum Institute, Johannesburg, South Africa.
D MudzengiThe Aurum Institute, Johannesburg, South Africa.
S CharalambousThe Aurum Institute, Johannesburg, South Africa.
C M Chetty-MakkanThe Aurum Institute, Johannesburg, South Africa.
H Kisbey-GreenThe Aurum Institute, Johannesburg, South Africa.
M MaraisaneThe Aurum Institute, Johannesburg, South Africa.
J GrundCenters for Disease Control and Prevention, Atlanta, GA, USA.
Aurum Institute · ZAUniversity of the Witwatersrand · ZACenters for Disease Control and Prevention · USSpelman College · US

Funding

CGH CDC HHS 6546
6 · The paper itself

Abstract

backgroundStudies estimate that circumcising men between the ages of 20-30 years who have exhibited previous risky sexual behaviour could reduce overall HIV prevalence. Demand creation strategies for medical male circumcision (MMC) targeting men in this age group may significantly impact these prevalence rates.

objectivesThe objective of this study is to evaluate the cost-effectiveness and cost-benefit of an implementation science, pre-post study designed to increase the uptake of male circumcision for ages 25-49 at a fixed MMC clinic located in Gauteng Province, South Africa.

methodsA health care provider perspective was utilised to collect all costs. Costs were compared between the standard care scenario of routine outreach strategies and a full intervention strategy. Cost-effectiveness was measured as cost per mature man enrolled and cost per mature man circumcised. A cost-benefit analysis was employed by using the Bernoulli model to estimate the cases of HIV averted due to medical male circumcision (MMC), and subsequently translated to averted medical costs.

resultsIn the 2015 intervention, the cost of the intervention was $9445 for 722 men. The total HIV treatment costs averted due to the intervention were $542,491 from a public care model and $378,073 from a private care model. The benefit-cost ratio was 57.44 for the public care model and 40.03 for the private care model. The net savings of the intervention were $533,046 or $368,628 - depending on treatment in a public or private setting.

conclusionsThe intervention was cost-effective compared to similar MMC demand interventions and led to statistically significant cost savings per individual enrolled.

Indexed as

Circumcision, MaleHIV InfectionsAdultCost-Benefit AnalysisHumansMaleMiddle AgedSexual BehaviorSouth AfricaYoung AdultCost-benefit analysisCost-effectiveness analysisDemand creationHIVMedical male circumcision

Identifiers

PMID34654429
PMCPMC8520207
OpenAlexW3205447639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.