Evidence map›Paper›PMID 34654375›Full record

ArticleBMC geriatrics2021

Longitudinal study: understanding the lived experience of couples across the trajectory of dementia.

Mary S Mittelman, Maureen K O'Connor, Tiffany Donley, Cynthia Epstein-Smith, Andrew Nguyen, Roscoe Nicholson, Rebecca Salant, Steven D Shirk, Elizabeth Stevenson

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04863495 (A Multi-Center Observational Study of Couples Across the Trajectory of Dementia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04863495 completednot on this map

A Multi-Center Observational Study of Couples Across the Trajectory of Dementia

TypeobservationalSponsorNYU Langone HealthRan2021 to 2026Enrolled544ConditionsAlzheimer Disease, Dementia of Alzheimer Type
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mary S MittelmanDepartment of Psychiatry, New York University School of Medicine, New York, USA. mary.mittelman@nyulangone.org.ORCID 0000-0002-4074-8537
Maureen K O'ConnorDepartment of Neurology, Boston University School of Medicine, Boston, MA, USA.
Tiffany DonleyDepartment of Population Health, New York University School of Medicine, New York, USA.
Cynthia Epstein-SmithDepartment of Psychiatry, New York University School of Medicine, New York, USA.
Andrew NguyenDepartment of Neurology, Boston University School of Medicine, Boston, MA, USA.
Roscoe NicholsonDepartment of Human Development, University of Chicago, Chicago, IL, USA.
Rebecca SalantDepartment of Psychiatry, New York University School of Medicine, New York, USA.
Steven D ShirkDepartment of Psychiatry and Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Elizabeth StevensonDepartment of Psychiatry, New York University School of Medicine, New York, USA.
New York University · USBoston University · USUniversity of Chicago · USUniversity of Massachusetts Chan Medical School · US

Funding

Research Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4M
Understanding the lived experience of couples across the trajectory of dementiaR01AG062684 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MITTELMAN, MARY SHERMAN, O'CONNOR, MAUREEN KATHELEEN · 2019 to 2023
$3.3M
NIA NIH HHS P30 AG066512NIA NIH HHS R01 AG062684NIA NIH HHS R01 AG062684-01
6 · The paper itself

Abstract

backgroundThe longitudinal study, "Couples Lived Experiences," focuses on whether and how relationship characteristics of older couples change with the cognitive decline of one member of the couple, and how these changes affect each individual's emotional and physical health outcomes. Until now, most psychosocial research in dementia has focused either on the person with dementia (PWD) or the caregiver separately. The previous literature examining relationship characteristics and their role in outcomes for the caregiver and PWD is scant and suffers from methodological issues that limit the understanding of which relationship characteristics most influence outcomes for caregivers and care-receivers and what other factors may mitigate or exacerbate their effects.

methodsWe will enroll 300 dyads and collect information via online interviews of each member of the couple, every 6 months for 3 years. Relationship characteristics will be measured with a set of short, well-validated, and reliable self-report measures, plus the newly developed "Partnership Approach Questionnaire." Outcomes include global quality of life, subjective physical health, mental health (depression and anxiety), and status change (transitions in levels of care; i.e., placement in a nursing home). Longitudinal data will be used to investigate how relationship characteristics are affected by cognitive, functional, and behavioral changes, and the impact of these changes on health outcomes. Qualitative data will also be collected to enrich the interpretation of results of quantitative analyses. DISCUSSION: Psychosocial interventions have demonstrated effectiveness in promoting the wellbeing of PWD and their caregivers. The knowledge gained from this study can lead to the development or enhancement of targeted interventions for older couples that consider the impact of cognitive and functional decline on the relationship between members of a couple and thereby improve their wellbeing.

trial registrationThis study has been registered with ClinicalTrials.gov. ClinicalTrials.gov Identifier is: NCT04863495 .

Indexed as

DementiaQuality of LifeCaregiversHumansLongitudinal StudiesMental HealthAlzheimer’sCouplesDementiaOlder adultsPsychosocial factorsRelationships

Identifiers

PMID34654375
PMCPMC8518196
OpenAlexW3207912253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.