Evidence map›Paper›PMID 34654283›Full record

ArticleEuropean geriatric medicine2018

Feasibility of optimizing pharmacotherapy in heart failure patients admitted to an acute geriatric ward: role of the clinical pharmacist.

Karolien Walgraeve, Lorenz Van der Linden, Johan Flamaing, Katleen Fagard, Isabel Spriet, Jos Tournoy

Registry-linked trialAbstract read
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In one paragraph

Article in European geriatric medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02149940 (Feasibility of Pharmaceutical Interventions in Elderly Heart Failure Patients), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02149940 nacompletednot on this map

Feasibility of Pharmaceutical Interventions in Elderly Heart Failure Patients: a Pilot Study.

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2013 to 2013Enrolled29ConditionsHeart FailureArmsheart-failure related pharmaceutical intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Empowering European hospital pharmacists in the face of heart failure.European journal of hospital pharmacy : science and practice · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karolien Walgraeve *Pharmacy Department, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium. karolien.walgraeve@uzleuven.be.
Lorenz Van der Linden *Pharmacy Department, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
Johan FlamaingDepartment of Geriatric Medicine, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
Katleen FagardDepartment of Geriatric Medicine, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
Isabel SprietPharmacy Department, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
Jos TournoyDepartment of Geriatric Medicine, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHeart failure is associated with high mortality and (re)hospitalization rates. Multidisciplinary teams involving pharmacists are effective in preventing disease-related adverse outcomes such as heart-failure-related hospitalizations. We aimed to investigate the impact of integrating clinical pharmacists into a multidisciplinary care team on drug therapies in geriatric heart failure patients. Additionally, we wished to standardize the clinical pharmacy intervention by developing a comprehensive algorithm.

methodsA prospective feasibility study was conducted in which systematic pharmaceutical recommendations in a geriatric heart failure population were given. Inclusion criteria were admission to the acute geriatric ward, a minimum age of 75 years and a diagnosis of heart failure. The number of pharmaceutical recommendations, the acceptance rate by the treating physician and the patients' clinical tolerability of the recommendations were registered. Six months after discharge, the general practitioner was contacted to determine drug therapy and heart-failure-related clinical outcomes. We developed a comprehensive algorithm to provide a structured, step-by-step approach for the pharmacotherapeutic evaluation of older heart failure patients.

resultsThirty patients were included over a 5-month period; one patient dropped out. Sixty-one pharmaceutical recommendations were formulated for the treating physicians of which 43 were accepted. Five recommendations were not tolerated by the patients. The majority of the recommendations regarded diuretic therapy. The final algorithm was considered to contain the basic items needed to provide a comprehensive pharmacotherapeutic evaluation.

conclusionsA clinical pharmacist can play an important role in the optimization of therapy for HF patients in a geriatric ward.

trial registrationClinicaltrials.gov NCT02149940.

Indexed as

Clinical pharmacyGeriatric inpatientHeart failureMultidisciplinary team

Identifiers

PMID34654283
OpenAlexW2782170604

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.