Evidence map›Paper›PMID 34654268›Full record

ArticleEuropean geriatric medicine2018

Self-reported fatigue as a risk index for dementia diagnosis.

Symeon H Panagiotakis, Panagiotis Simos, Ioannis Zaganas, Maria Basta, Garyfalia S Perysinaki, Nikolaos Fountoulakis, Maria Giaka, Stefania Kapetanaki, Irini Koutentaki, Antonios Bertsias and 6 more

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Article in European geriatric medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Symeon H PanagiotakisInternal Medicine Department, Heraklion University Hospital, Voutes, 71003, Heraklion, Crete, Greece. simeongpan@hotmail.com.
Panagiotis SimosPsychiatry Department, Medical School, University of Crete, Heraklion, Crete, Greece.
Ioannis ZaganasNeurology Department, Medical School, University of Crete, Heraklion, Crete, Greece.
Maria BastaPsychiatry Department, Medical School, University of Crete, Heraklion, Crete, Greece.
Garyfalia S PerysinakiRethymnon General Hospital, Rethymnon, Crete, Greece.
Nikolaos FountoulakisInternal Medicine Department, Heraklion University Hospital, Voutes, 71003, Heraklion, Crete, Greece.
Maria GiakaInternal Medicine Department, Heraklion University Hospital, Voutes, 71003, Heraklion, Crete, Greece.
Stefania KapetanakiNeurology Department, Medical School, University of Crete, Heraklion, Crete, Greece.
Irini KoutentakiPsychiatry Department, Medical School, University of Crete, Heraklion, Crete, Greece.
Antonios BertsiasClinic of Social and Family Medicine, Medical School, University of Crete, Heraklion, Crete, Greece.
George DuijkerClinic of Social and Family Medicine, Medical School, University of Crete, Heraklion, Crete, Greece.
Nikolaos ScarmeasNeurology Department, Medical School, University of Athens, Athens, Greece.
Chariklia TzirakiMELABEV, Research Institute, Community Elders Clubs and Institute for Gerontological Data Bases, Hebrew University, Jerusalem, Israel.
Christos LionisClinic of Social and Family Medicine, Medical School, University of Crete, Heraklion, Crete, Greece.
Alexandros VgontzasPsychiatry Department, Medical School, University of Crete, Heraklion, Crete, Greece.
Dimitrios T Boumpas4th Department of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCognitive impairment and frailty are major problems of older age. This study aims to explore the association between frailty and cognitive impairment in a rural cohort of older subjects in southern Europe (Cretan Aging Cohort).

methodsCommunity-based, primary care, cross-sectional, study in the Heraklion Prefecture, Crete, Greece. Four hundred and two persons aged 60-100 years from the Cretan Aging Cohort [100 with dementia, 175 with mild cognitive impairment (MCI) and 127 cognitively non-impaired] were enrolled, mostly rural dwellers (86.2%). Frailty was assessed with the Simple "Frail" Questionnaire Screening Tool. Demographic data, BMI, Mini-Mental State Examination scores (MMSE), severity of dementia according to the Clinical Dementia Rating Scale, and depressive symptoms according to the Geriatric Depression Scale (GDS) were recorded.

resultsFrailty was present in 17% of persons with dementia (73.8% of mild severity), in 6.3% of persons with MCI and in 8.7% of cognitively non-impaired persons (P < 0.05). Among the various frailty variables, fatigue and difficulty walking were significantly more frequently reported by persons with dementia. Each frailty variable and the frailty score correlated negatively with MMSE score and positively with GDS score and polypharmacy. Multivariate analysis revealed that reported fatigue improved the identification of dementia in addition to MMSE, significantly and independently of symptoms of depression (P = 0.04).

conclusionFrailty rates are significantly higher in persons with dementia. In this predominantly rural cohort of older subjects, reported fatigue could serve as a marker of physical decline and a complementary index for referral for further neuropsychological and neuropsychiatric evaluation.

Indexed as

Cognitive impairmentFatigueFrailty

Identifiers

PMID34654268

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