Evidence map›Paper›PMID 34654255›Full record

ArticleEuropean geriatric medicine2018

Health-related quality of life as a predictor of mortality in heterogeneous samples of older adults.

Helena Liira, Nahal Mavaddat, Maija Eineluoto, Hannu Kautiainen, Timo Strandberg, Merja Suominen, Marja-Liisa Laakkonen, Ulla Eloniemi-Sulkava, Harri Sintonen, Kaisu Pitkälä

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Article in European geriatric medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. The impact of loneliness and social isolation on health state utility values: a systematic literature review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Helena LiiraDepartment of General Practice, University of Helsinki, Helsinki, Finland. helena.liira@helsinki.fi.
Nahal MavaddatGeneral Practice, School of Primary, Aboriginal and Rural Health Care, University of Western Australia, Perth, Australia.
Maija EineluotoDepartment of General Practice, University of Helsinki, Helsinki, Finland.
Hannu KautiainenDepartment of General Practice, University of Helsinki, Helsinki, Finland.
Timo StrandbergGeriatric Clinic, Department of Medicine, University of Helsinki, Helsinki, Finland.
Merja SuominenDepartment of General Practice, University of Helsinki, Helsinki, Finland.
Marja-Liisa LaakkonenDepartment of General Practice, University of Helsinki, Helsinki, Finland.
Ulla Eloniemi-SulkavaCentre for Continuing Education, University of Helsinki, Helsinki, Finland.
Harri SintonenDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Kaisu PitkäläDepartment of General Practice, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth-related quality of life (HRQoL) is associated with survival in older people with multimorbidities and disabilities. However, older people differ in their characteristics, and less is known about whether HRQoL predicts survival in heterogeneous older population samples differing in their functional, cognitive, psychological or social disabilities. The aim of this study was to explore HRQoL in heterogeneous samples of older men and women, and to explore its prognostic significance for mortality.

methodsWe analysed combined individual patient data from eight heterogeneous study samples all of which were assessed with the same methods. We used 15D, a generic, comprehensive instrument for measuring HRQoL, which provides a single index in addition to a profile. Two-year mortality was retrieved from central registers.

resultsHealth-related quality of life measurements with 15D were available for 3153 older adults. The mean HRQoL was highest among older businessmen (0.878) and lowest among nursing home residents (0.601). 15D predicted independently and significantly the 2-year survival in the total sample [hazard ratio (HR)/SD 0.44, 95% CI 0.40-0.48)]. However, 15D did not predict mortality in samples of spousal caregivers, lonely older adults and cardiovascular patients.

conclusions15D captures health and disability factors associated with prognosis whereas in older populations suffering from psychological and social impairments such as caregiver burden or loneliness HRQoL may not reflect their health risks.

Indexed as

Health-related quality of lifeMortalityOlder adults

Identifiers

PMID34654255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.