Evidence map›Paper›PMID 34653873›Full record

ArticleRespiratory medicine

A new standard scoring for interstitial pneumonia based on quantitative analysis of ultrasonographic data: A study on COVID-19 patients.

Fiorella Anna Lombardi, Roberto Franchini, Rocco Morello, Ernesto Casciaro, Stefania Ianniello, Maurizio Serra, Francesco Satriano, Francesco Mojoli, Silvia Mongodi, Daniela Pignatelli and 2 more

Abstract read
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Article in Respiratory medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fiorella Anna LombardiNational Research Council - Institute of Clinical Physiology, Lecce, Italy. Electronic address: fiorella@ifc.cnr.it.
Roberto FranchiniNational Research Council - Institute of Clinical Physiology, Lecce, Italy.
Rocco MorelloNational Research Council - Institute of Clinical Physiology, Lecce, Italy.
Ernesto CasciaroNational Research Council - Institute of Clinical Physiology, Lecce, Italy.
Stefania IannielloDiagnostic Imaging Unit, National Institute for Infectious Diseases "L. Spallanzani" IRCCS, Rome, Italy.
Maurizio SerraPneumology Unit 2, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Francesco SatrianoPneumology Unit 2, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Francesco MojoliDepartment of clinical-surgical, diagnostic and pediatric sciences, Unit of anesthesia and intensive care, University of Pavia, Pavia, Italy; Anesthesia and Intensive Care, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy.
Silvia MongodiAnesthesia and Intensive Care, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy.
Daniela PignatelliNational Research Council - Institute of Clinical Physiology, Lecce, Italy.
Marco Di PaolaNational Research Council - Institute of Clinical Physiology, Lecce, Italy.
Sergio CasciaroNational Research Council - Institute of Clinical Physiology, Lecce, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effectiveness of 3 novel lung ultrasound (LUS)-based parameters: Pneumonia Score and Lung Staging for pneumonia staging and COVID Index, indicating the probability of SARS-CoV-2 infection.

methodsAdult patients admitted to the emergency department with symptoms potentially related to pneumonia, healthy volunteers and clinical cases from online accessible databases were evaluated. The patients underwent a clinical-epidemiological questionnaire and a LUS acquisition, following a 14-zone protocol. For each zone, a Pneumonia score from 0 to 4 was assigned by the algorithm and by an expert operator (kept blind with respect to the algorithm results) on the basis of the identified imaging signs and the patient Lung Staging was derived as the highest observed score. The output of the operator was considered as the ground truth. The algorithm calculated also the COVID Index by combining the automatically identified LUS markers with the questionnaire answers and compared with the nasopharyngeal swab results.

resultsOverall, 556 patients were analysed. A high agreement between the algorithm assignments and the expert operator evaluations was observed, both for Pneumonia Score and Lung Staging, with the latter having sensitivity and specificity over 92% both in the discrimination between healthy/sick patients and between sick patients with mild/severe pneumonia. Regarding the COVID Index, an area under the curve of 0.826 was observed for the classification of patients with/without SARS-CoV-2.

conclusionThe proposed methodology allowed the identification and staging of patients suffering from pneumonia with high accuracy. Moreover, it provided the probability of being infected by SARS-CoV-2.

Indexed as

AdolescentAdultAgedAged, 80 and overCOVID-19Databases, FactualFemaleHumansLungLung Diseases, InterstitialMaleMiddle AgedResearch DesignSensitivity and SpecificitySurveys and QuestionnairesUltrasonographyCOVID IndexLung stagingLung ultrasoundPneumoniaPneumonia scoreSARS-CoV-2

Identifiers

PMID34653873
PMCPMC8496946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.