Evidence map›Paper›PMID 34653617›Full record

ArticleInternational journal of antimicrobial agents2021

Variability in oral antibiotic step-down therapy in the management of Gram-negative bloodstream infections.

Joshua T Thaden, Pranita D Tamma, Yohei Doi, Nick Daneman, Antibacterial Resistance Leadership Group (ARLG)

Open access · greenAbstract read
In one paragraph

Article in International journal of antimicrobial agents, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Joshua T ThadenDivision of Infectious Diseases, Duke University School of Medicine, DUMC Box 102359, Durham, NC 27701, USA. Electronic address: joshua.thaden@duke.edu.
Pranita D TammaDepartment of Pediatrics, Johns Hopkins University School of Medicine, 1800 Orleans Street, Sheikh Zayed Tower, Baltimore, MD 21287, USA.
Yohei DoiCenter for Innovative Antimicrobial Therapy, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Scaife Hall, Suite 829, 3550 Terrace Street, Pittsburgh, PA 15213, USA; Departments of Microbiology and Infectious Diseases, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan.
Nick DanemanSunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Room G1 06, Toronto, ON, Canada M4N 3M5.
Antibacterial Resistance Leadership Group (ARLG)
Duke University · USFujita Health University · JPJohns Hopkins University · USSunnybrook Health Science Centre · CA

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Institutional Career Development CoreKL2TR002554 · NCATS · DUKE UNIVERSITY · PI SVETKEY, LAURA P · 2018 to 2022
$8.2M
NCATS NIH HHS KL2 TR002554NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

There are important gaps in the literature regarding the role and timing of oral therapy for Gram-negative bloodstream infections (GN-BSIs). To better understand contemporary management practices involving oral step-down in GN-BSI, we conducted an international survey of infectious diseases (ID) specialists. We developed and disseminated an online survey to ID specialists to assess practice patterns involving oral step-down in GN-BSIs, including providers from six continents and 28 countries. χ

Indexed as

Administration, IntravenousAdministration, OralAnti-Bacterial AgentsBacteremiaCross InfectionGram-Negative Bacterial InfectionsHumansPractice Patterns, Physicians'Surveys and QuestionnairesAnti-Bacterial AgentsBacteraemiaBloodstream infectionGram-negativeOral step-down

Identifiers

PMID34653617
PMCPMC8645249
OpenAlexW3207958455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.