Evidence map›Paper›PMID 34653608›Full record

Trial reportEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists2021

Treatment With 25-Hydroxyvitamin D

Zhila Maghbooli, Mohammad Ali Sahraian, Saeidreza Jamalimoghadamsiahkali, Asma Asadi, Azadeh Zarei, Abolfazl Zendehdel, Tarlan Varzandi, Sara Mohammadnabi, Neda Alijani, Mehrdad Karimi and 2 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 13 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 13 syntheses or guidelines pooled it, 100 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Zhila MaghbooliMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Ali SahraianMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Saeidreza JamalimoghadamsiahkaliDepartment of Infectious Disease, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Asma AsadiDepartment of Infectious Disease, Shohada Pakdasht Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azadeh ZareiDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Abolfazl ZendehdelDepartment of Geriatric Medicine, Ziaeian Hospital, Tehran University of Medical Scinces, Tehran, Iran.
Tarlan VarzandiMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Sara MohammadnabiMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Neda AlijaniDepartment of Infectious Disease, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mehrdad KarimiDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Arash ShirvaniVitamin D, Skin and Bone Research Laboratory, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Michael F HolickVitamin D, Skin and Bone Research Laboratory, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts. Electronic address: mfholick@bu.edu.
Tehran University of Medical Sciences · IRBoston University · USShahid Beheshti University of Medical Sciences · IRShariati Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe goal of this randomized, double-blinded, placebo-controlled clinical trial was to investigate the therapeutic efficacy of oral 25-hydroxyvitamin D

methodsThis is a multicenter, randomized, double-blinded, placebo-controlled clinical trial. Participants were recruited from 3 hospitals that are affiliated to [Institution Blinded for Review] and [Institution Blinded for Review].

resultsA total 106 hospitalized patients who had a circulating 25(OH)D

conclusionOur analysis indicated that oral 25(OH)D

Indexed as

COVID-19Vitamin D DeficiencyCalcifediolCholecalciferolDietary SupplementsDouble-Blind MethodHumansNeutrophilsSARS-CoV-2Severity of Illness IndexVitamin D25-hydroxyvitamin DCalcifediolCholecalciferolVitamin D25-hydroxyvitamin D(3)COVID-19lymphocytesupplementationviral infectionvitamin D deficiency

Identifiers

PMID34653608
PMCPMC8511889
OpenAlexW3205398273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.