Evidence map›Paper›PMID 34653501›Full record

ArticlePreventive medicine2021

Growing racial/ethnic disparities in overdose mortality before and during the COVID-19 pandemic in California.

Joseph Friedman, Helena Hansen, Ricky N Bluthenthal, Nina Harawa, Ayana Jordan, Leo Beletsky

Abstract read
In one paragraph

Article in Preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. The Contribution of Homelessness to Opioid Overdose Mortality and Associated Racial Disparities.Journal of urban health : bulletin of the New York Academy of Medicine · 2026
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  17. Coping mechanisms during the COVID-19 pandemic and lockdown in metropolitan Johannesburg, South Africa: A qualitative study.American journal of human biology : the official journal of the Human Biology Council · 2023
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph FriedmanMedical Informatics Home Area, University of California, Los Angeles, United States of America; Center for Social Medicine and Humanities, University of California, Los Angeles, United States of America. Electronic address: Joseph.robert.friedman@gmail.com.
Helena HansenCenter for Social Medicine and Humanities, University of California, Los Angeles, United States of America.
Ricky N BluthenthalDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, United States of America.
Nina HarawaDavid Geffen School of Medicine, University of California, Los Angeles, United States of America.
Ayana JordanDepartment of Psychiatry, School of Medicine, Yale University, United States of America.
Leo BeletskySchool of Law, Department of Health Sciences, and Health in Justice Action Lab, Northeastern University, United States of America.

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9M
NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR001881NIGMS NIH HHS T32 GM008042NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

As overdose mortality is spiking during the COVID-19 pandemic, few race/ethnicity-stratified trends are available. This is of particular concern as overdose mortality was increasing most rapidly in Black and Latinx communities prior to the pandemic. We used quarterly, age-standardized overdose mortality rates from California to assess trends by race/ethnicity and drug involved over time. Rates from 2020 Q2-Q4 were compared to expected trends based on ARIMA forecasting models fit using data from 2006 to 2020 Q1. In 2020 Q2-Q4 overdose death rates rose by 49.8% from 2019, exceeding an expected increase of 11.5% (95%CI: 0.5%-22.5%). Rates significantly exceeded forecasted trends for all racial/ethnic groups. Black/African American individuals saw an increase of 52.4% from 2019, compared to 42.6% among their White counterparts. The absolute Black-White overdose mortality gap rose from 0.7 higher per 100,000 for Black individuals in 2018 to 4.8 in 2019, and further increased to 9.9 during the pandemic. Black overdose mortality in California was therefore 34.3% higher than that of White individuals in 2020 Q2-Q4. This reflects growing methamphetamine-, cocaine-, and fentanyl-involved deaths among Black communities. Growing racial disparities in overdose must be understood in the context of the unequal social and economic fallout from the COVID-19 pandemic, during which time Black communities have been subjected to the dual burden of disproportionate COVID-19 deaths and rising overdose mortality. Increased investments are required to ameliorate racial/ethnic disparities in substance use treatment, harm reduction, and the structural drivers of overdose, as part of the COVID-19 response and post-pandemic recovery efforts.

Indexed as

COVID-19EthnicityCaliforniaHumansPandemicsSARS-CoV-2COVID-19 pandemicFentanylMethamphetamineOverdoseRacial/ethnic disparitiesSubstance use

Identifiers

PMID34653501
PMCPMC8521065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.