Evidence map›Paper›PMID 34653435›Full record

ArticleGeneral and comparative endocrinology2021

Relationships between cortisol and urinary androgens in female titi monkeys (Plecturocebus cupreus).

Lynea R Witczak, Rocío Arias Del Razo, Alexander Baxter, Alan J Conley, Rebecca Cotterman, Madison Dufek, Leana R Goetze, Allison R Lau, Sally P Mendoza, Logan E Savidge and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in General and comparative endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Lynea R WitczakDepartment of Psychology, University of California, Davis, United States; California National Primate Research Center, University of California, Davis, United States.
Rocío Arias Del RazoDepartment of Psychology, University of California, Davis, United States; California National Primate Research Center, University of California, Davis, United States.
Alexander BaxterDepartment of Psychology, University of California, Davis, United States; California National Primate Research Center, University of California, Davis, United States.
Alan J ConleyDepartment of Population Health and Reproduction, University of California, Davis, United States.
Rebecca CottermanDepartment of Population Health and Reproduction, University of California, Davis, United States.
Madison DufekCalifornia National Primate Research Center, University of California, Davis, United States.
Leana R GoetzeCalifornia National Primate Research Center, University of California, Davis, United States.
Allison R LauCalifornia National Primate Research Center, University of California, Davis, United States; Graduate Program in Animal Behavior, University of California, Davis, United States.
Sally P MendozaDepartment of Psychology, University of California, Davis, United States; California National Primate Research Center, University of California, Davis, United States.
Logan E SavidgeDepartment of Psychology, University of California, Davis, United States; California National Primate Research Center, University of California, Davis, United States.
Karen L BalesDepartment of Psychology, University of California, Davis, United States; California National Primate Research Center, University of California, Davis, United States; Department of Neurobiology, Physiology, and Behavior, University of California, Davis, United States; Graduate Program in Animal Behavior, University of California, Davis, United States. Electronic address: klbales@ucdavis.edu.
University of California, Davis · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
THE NEURAL BASIS OF PAIR-BONDING IN FEMALE TITI MONKEYSR01HD092055 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BALES, KAREN L. · 2017 to 2021
$2.8M
Neurobiological Mechanisms of Social Bonding in a Monogamous PrimateR01HD053555 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BALES, KAREN L. · 2009 to 2013
$2.1M
NICHD NIH HHS R01 HD053555NICHD NIH HHS R01 HD092055NIH HHS P51 OD011107
6 · The paper itself

Abstract

Steroid hormones are critical to the regulation of sociosexual behavior. Their role in the formation of pair bonds is complicated by the relative scarcity of this social system in mammals, as well as species and taxonomic differences in endocrine systems. In the present study, we experimentally manipulated the hypothalamic-pituitary-adrenal axis in female titi monkeys (Plecturocebus cupreus), a neotropical monkey studied for its strong, selective pair bonds. We validated an assay for plasma and urinary cortisol in this species, showing a strong suppression of cortisol following dexamethasone injection, and a significant but somewhat blunted response to adrenocorticotrophin hormone (ACTH) stimulation. Urinary androgens did not change in response to dexamethasone or ACTH. Plasma and urinary cortisol were moderately correlated, whereas urinary cortisol and androgens were only correlated when extreme cortisol values were included. In this study, we laid groundwork for studying the role of glucocorticoids and androgens (and eventually, their interactions with peptides) in the behavioral endocrinology of pair bonds in female titi monkeys.

Indexed as

HydrocortisoneHypothalamo-Hypophyseal SystemAndrogensAnimalsCallicebusDexamethasoneFemalePituitary-Adrenal SystemAndrogensDexamethasoneHydrocortisonePair bondsSocial monogamySteroid/peptide theory

Identifiers

PMID34653435
PMCPMC9250648
OpenAlexW3207156865

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.