Evidence map›Paper›PMID 34653247›Full record

ReviewThe journals of gerontology. Series A, Biological sciences and medical sciences2022

Bridging the Gap: A Geroscience Primer for Neuroscientists With Potential Collaborative Applications.

Jessica M Hoffman, Caesar M Hernandez, Abbi R Hernandez, Jennifer L Bizon, Sara N Burke, Christy S Carter, Thomas W Buford

Open access · greenAbstract readReview
In one paragraph

Review in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Translational Geroscience Strategies for Delaying Multimorbidity.ACS pharmacology & translational science · 2026
    Review
  2. Neurobiology of Aging: New Insights From Across the Research Spectrum.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  3. Article
  4. A Neuroscience Primer for Integrating Geroscience With the Neurobiology of Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jessica M HoffmanDepartment of Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Caesar M HernandezDepartment of Cellular, Development, and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-9690-5119
Abbi R HernandezDepartment of Medicine, Division of Gerontology, Geriatrics and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-3855-4047
Jennifer L BizonDepartment of Neuroscience and Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida, USA.
Sara N BurkeDepartment of Neuroscience and Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida, USA.
Christy S CarterDepartment of Medicine, Division of Gerontology, Geriatrics and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-9657-3193
Thomas W BufordDepartment of Medicine, Division of Gerontology, Geriatrics and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USUniversity of Florida · US

Funding

Sex hormones and arthritis in a long lived animal modelP30AG050886 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Daniel L Smith · 2015 to 2026
$11.3M
Interdisciplinary Training in Pathobiology and Rehabilitation Medicine.T32HD071866 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES RIMMER, Anna E. Thalacker-Mercer · 2012 to 2026
$4.8M
Metabolic Interventions for Enhancing Cognitive Resilience in Aging and Alzheimers DiseaseRF1AG060977 · NIA · UNIVERSITY OF FLORIDA · PI BURKE, SARA N · 2019 to 2019
$1.9M
The metabolomic consequences of small size and long lifeR00AG059920 · NIA · AUGUSTA UNIVERSITY · PI HOFFMAN, JESSICA MARIE · 2022 to 2024
$742k
Interconnections among Cognition, Pain, and Physical Function in Aging.K02AG062498 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BUFORD, THOMAS W · 2020 to 2024
$524k
The metabolomic consequences of small size and long lifeK99AG059920 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HOFFMAN, JESSICA MARIE · 2019 to 2021
$342k
NIA NIH HHS K02 AG062498NIA NIH HHS K99 AG059920NIA NIH HHS K99AG059920NIA NIH HHS P30 AG050886NIA NIH HHS R00 AG059920NIA NIH HHS RF1 AG060977NICHD NIH HHS T32 HD071866NICHD NIH HHS T32HD071866
6 · The paper itself

Abstract

While neurodegenerative diseases can strike at any age, the majority of afflicted individuals are diagnosed at older ages. Due to the important impact of age in disease diagnosis, the field of neuroscience could greatly benefit from the many of the theories and ideas from the biology of aging-now commonly referred as geroscience. As discussed in our complementary perspective on the topic, there is often a "silo-ing" between geroscientists who work on understanding the mechanisms underlying aging and neuroscientists who are studying neurodegenerative diseases. While there have been some strong collaborations between the biology of aging and neuroscientists, there is still great potential for enhanced collaborative effort between the 2 fields. To this end, here, we review the state of the geroscience field, discuss how neuroscience could benefit from thinking from a geroscience perspective, and close with a brief discussion on some of the "missing links" between geroscience and neuroscience and how to remedy them. Notably, we have a corresponding, concurrent review from the neuroscience perspective. Our overall goal is to "bridge the gap" between geroscience and neuroscience such that more efficient, reproducible research with translational potential can be conducted.

Indexed as

AgingGeroscienceHumansCognitive declineFrailtyLife-span–extending interventionsResilience

Identifiers

PMID34653247
PMCPMC8751800
OpenAlexW3207014331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.