ArticlePloS one2021
Variation of tuberculosis prevalence across diagnostic approaches and geographical areas of Indonesia.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Clinical outcomes and surgical strategy for spine tuberculosis: a systematic review and meta-analysis.Spine deformity · 2024Pooled it
- Tuberculosis in Sudan: systematic review and meta analysis.BMC pulmonary medicine · 2024Pooled it
- COVID-19 disruptions and spring surges: an interrupted time-series analysis of tuberculosis diagnostic challenges in Northeast Iran.Scientific reports · 2026Article
- Article
- Diagnostic Modality Influences Tuberculosis Detection in People Living with HIV: Eight Years of Data from a Thai Referral Center.Diagnostics (Basel, Switzerland) · 2025Article
- Further analysis of tuberculosis in eight high-burden countries based on the Global Burden of Disease Study 2021 data.Infectious diseases of poverty · 2024Article
- Non-communicable comorbidities in pulmonary tuberculosis and healthcare utilization: a cross-sectional study of 2021 Indonesian national health insurance data.Archives of public health = Archives belges de sante publique · 2024Article
- Rifampicin Resistant Tuberculosis Among Presumptive Pulmonary Tuberculosis in Province Referral Hospital, Indonesia: Dynamic Cases of a 7-Year Report.Journal of research in health sciences · 2024Article
- First detection of bovine tuberculosis by Ziehl-Neelsen staining and polymerase chain reaction at dairy farms in the Lekok Sub-District, Pasuruan Regency, and Surabaya region, Indonesia.Veterinary world · 2024Article
- Development of a multiassay algorithm (MAA) to identify recent HIV infection in newly diagnosed individuals in Indonesia.iScience · 2023Article
- The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach.PloS one · 2023Article
- One-stage anterior approach for long-segment subaxial cervical spondylitis tuberculosis: A case report.International journal of surgery case reports · 2022Article
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTuberculosis (TB) has contributed to a significant disease burden and economic loss worldwide. Given no gold standard for diagnosis, early identification of TB infection has been challenging. This study aimed to comparatively investigate the prevalence of TB across diagnostic approaches (sputum AFB, sputum culture, sputum genetic test, and chest x-ray) and geographical areas of Indonesia.
methodsParticipant demographic variables and TB screening test results were obtained from the Tuberculosis Unit, Health Research and Development Agency, Ministry of Health (HRDA-MoH). The prevalence of pulmonary TB in populations aged 15 years and over was calculated using TB cases as a numerator and populations aged 15 years and over as a denominator. Variations across geographical areas and diagnostic approaches were expressed as prevalence and 95% confidence interval (CI).
resultsA total of 67,944 records were reviewed. Based on bacteriological evidence, the prevalence of TB per 100,000 in Indonesia was 759 (95% CI: 589.7-960.8) with variations across areas: 913 (95% CI 696.7-1,176.7; Sumatra), 593 (95% CI 447.2-770.6; Java-Bali), and 842 (95% CI 634.7-1,091.8; other islands). Also, the prevalence of TB varied across diagnostic approaches: 256.5 (sputum AFB), 545 (sputum culture), 752.2 (chest x-ray), and 894.9 (sputum genetic test). Based on sputum AFB, the TB prevalence varied from 216.6 (95% CI 146.5-286.8; Java-Bali), 259.9 (95% CI 184.2-335.6; other islands) to 307.4 (95% CI 208.3-406.5; Sumatra). Based on sputum culture, the TB prevalence ranged from 487.9 (95% CI 433.6-548.6; Java-Bali), 635.9 (95% CI 564.9-715.1; Sumatra), to 2,129.8 (95% CI 1,664.0-2,735.6; other islands). Based on chest x-ray, the TB prevalence varied from 152.1 (95% CI 147.9-156.3; Java-Bali), 159.2 (95% CI 154.1-164.3; Sumatra), to 864 (95% CI 809-921.4; other islands). Based on sputum genetic test, the TB prevalence ranged from 838.7 (95% CI 748.4-900.8; Java-Bali), 875 (95% CI 775.4-934.2; Sumatra), to 941.2 (95% CI 663.6-992.3; other islands).
conclusionsThe variation of TB prevalence across geographical regions could be confounded by the diagnostic approaches.
trial registrationThis study was approved by the Institutional Review Board of Chulalongkorn University (IRB No. 684/63).
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