Evidence map›Paper›PMID 34652699›Full record

ReviewEuropean geriatric medicine2019

Association between sarcopenia and diabetes: a systematic review and meta-analysis of observational studies.

Nicola Veronese, Damiano Pizzol, Jacopo Demurtas, Pinar Soysal, Lee Smith, Cornel Sieber, Timo Strandberg, Isabelle Bourdel-Marchasson, Alan Sinclair, Mirko Petrovic and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in European geriatric medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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  5. Prevalence, risk factors and adverse health outcomes of osteosarcopenia in middle-aged and older adults with type 2 diabetes mellitus-a scoping review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 7 countries.

Nicola VeroneseNational Research Council, Neuroscience Institute, Aging Branch. Via Giustiniani 2, 35128, Padua, Italy. ilmannato@gmail.com.ORCID http://orcid.org/0000-0002-9328-289X
Damiano PizzolOperational Research Unit, Doctors with Africa, Dar es Salaam, Mozambique.
Jacopo DemurtasPrimary Care Department, Azienda USL Toscana Sud Est, 58100, Grosseto, Italy.
Pinar SoysalDepartment of Geriatric Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Lee SmithThe Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, CB1 1PT, UK.
Cornel SieberInstitute for Biomedicine of Ageing (IBA), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 90408, Nuremberg, Germany.
Timo StrandbergUniversity of Helsinki, Clinicum and Helsinki University Hospital, Helsinki, Finland.
Isabelle Bourdel-MarchassonCNRS, University of Bordeaux, RMSB, Bordeaux, France.
Alan SinclairDiabetes Frail Ltd and King's College, London, UK.
Mirko PetrovicDepartment of Internal Medicine and Paediatrics, Section of Geriatrics, Ghent University, Ghent, Belgium.
Stefania MaggiNational Research Council, Neuroscience Institute, Aging Branch. Via Giustiniani 2, 35128, Padua, Italy.
Special Interest Groups of Systematic Reviews and Meta-Analysis for Healthy Ageing, Diabetes, Sarcopenia of European Geriatric Medicine Society (EuGMS)
Neuroscience Institute · ITBezmiâlem Vakıf Üniversitesi · TRCentre National de la Recherche Scientifique · FRDoctors with Africa Cuamm · ITFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGhent University Hospital · BEKing's College London · GBUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSarcopenia and diabetes are two common conditions in older people. Some recent literature has proposed that these two conditions can be associated. However, to date, no attempt has been made to collate this literature. Therefore, we aimed to summarize the prevalence of sarcopenia in diabetes (and vice versa) and the prevalence of sarcopenia in people with diabetes complications, through a systematic review and meta-analysis.

methodsTwo authors searched major electronic databases from inception until March 2019 for case control/cross-sectional/longitudinal studies investigating sarcopenia and diabetes. The strength of the reciprocal associations between sarcopenia and diabetes was assessed through odds ratios (ORs) with 95% confidence intervals (CIs), adjusted for potential confounders, where possible.

resultsFrom 953 potential eligible articles, 20 were included in the systematic review, with 17 providing data for meta-analysis. Overall, 54,676 participants were included (mean age = 65.4 years). Diabetic participants had an increased prevalence of sarcopenia compared to controls (n = 10; OR = 1.635; 95% CI 1.204-2.220; p = 0.002; I

conclusionsOur study suggests a bidirectional association between diabetes and sarcopenia, particularly when diabetic complications are present.

Indexed as

DiabetesMeta-analysisPhysical performanceSarcopenia

Identifiers

PMID34652699
OpenAlexW2953794514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.