ArticleEuropean geriatric medicine2019
The association between platelet indices, cognitive screening tests and functional dependence screening questionnaires in hospitalized older people.
Article in European geriatric medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Platelet Dynamics in Neurodegenerative Disorders: Investigating the Role of Platelets in Neurological Pathology.Journal of clinical medicine · 2024Review
- Health-Related Predictors of Changes in Cognitive Status in Community-Dwelling Older Individuals.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeActivated platelets have been suggested to play an important role in the pathogenesis of dementia. Recent studies have shown contradictory results concerning the relationship between blood platelet indices and cognitive performance.
methodsThis cross-sectional study evaluates the relationship between basic platelet indices and cognitive and functional performance of 754 men and women, aged 60-105 years old, admitted to the geriatric hospital unit. Assessment of global cognitive function and functional ability were performed using Mini-Mental State Examination, the seven-point Clock Drawing Test, the Katz Activities of Daily Living, the Lawton Instrumental Activities of Daily Living Scale and the Vulnerable Elders Survey Questionnaire. As platelet indices, platelet count, mean platelet volume, plateletcrit and platelet distribution width were measured.
resultsThere was no significant correlation between cognitive performance and platelet indices. Out of the functional dependence questionnaires, only the Katz Activities of Daily Living and the Vulnerable Elders Survey Questionnaire were weakly correlated with platelet count (r = - 0.080 and r = 0.096) and plateletcrit (r = - 0.075 and 0.082, respectively), but these associations diminished in sex-specific analyses.
conclusionsCognitive and functional status are not systematically related to platelet indices in multimorbid hospitalized older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.