Evidence map›Paper›PMID 34652551›Full record

ArticleEJNMMI research2021

Short-duration dynamic [

Dae-Myoung Yang, Ryan Alfano, Glenn Bauman, Jonathan D Thiessen, Joseph Chin, Stephen Pautler, Madeleine Moussa, Jose A Gomez, Irina Rachinsky, Mena Gaed and 3 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04009174 (Multi-modality Prostate Cancer Image Guided Interventions), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04009174 nacompletednot on this map

Multi-modality Prostate Cancer Image Guided Interventions

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2012 to 2023Enrolled52ConditionsProstate CancerArmsImaging Panel
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Dae-Myoung YangDepartment of Medical Biophysics, The University of Western Ontario, London, ON, Canada.ORCID http://orcid.org/0000-0002-1229-7759
Ryan AlfanoDepartment of Medical Biophysics, The University of Western Ontario, London, ON, Canada.
Glenn BaumanLondon Health Sciences Centre, London, ON, Canada.
Jonathan D ThiessenDepartment of Medical Biophysics, The University of Western Ontario, London, ON, Canada.
Joseph ChinLondon Health Sciences Centre, London, ON, Canada.
Stephen PautlerDepartment of Oncology, The University of Western Ontario, London, ON, Canada.
Madeleine MoussaLondon Health Sciences Centre, London, ON, Canada.
Jose A GomezLondon Health Sciences Centre, London, ON, Canada.
Irina RachinskyLondon Health Sciences Centre, London, ON, Canada.
Mena GaedDepartment of Pathology and Laboratory Medicine, The University of Western Ontario, London, ON, Canada.
Kevin J ChungDepartment of Medical Biophysics, The University of Western Ontario, London, ON, Canada.
Aaron WardDepartment of Medical Biophysics, The University of Western Ontario, London, ON, Canada.
Ting-Yim LeeDepartment of Medical Biophysics, The University of Western Ontario, London, ON, Canada. tlee@imaging.robarts.ca.ORCID http://orcid.org/0000-0001-7605-9752
Western University · CA

Funding

canada foundation of innovation Leading-Edge Fund
6 · The paper itself

Abstract

purposeLocalized prostate cancer (PCa) in patients is characterized by a dominant focus in the gland (dominant intraprostatic lesion, DIL). Accurate DIL identification may enable more accurate diagnosis and therapy through more precise targeting of biopsy, radiotherapy and focal ablative therapies. The goal of this study is to validate the performance of [

methodsMulti-modality image sets: in vivo T2-weighted (T2w)-MRI, 22-min dynamic [

results[

conclusionsWe have validated using co-registered digital histopathological images that parameters from kinetic analysis of 22-min dynamic [ CLINICAL TRIAL REGISTRATION NUMBER: NCT04009174 (ClinicalTrials.gov).

Indexed as

[18F]DCFPyLCT perfusionDominant intraprostatic lesion (DIL)Prostate-specific membrane antigen (PSMA)Tracer kinetic modelling

Identifiers

PMID34652551
PMCPMC8519985
OpenAlexW3179951239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.