Evidence map›Paper›PMID 34652274›Full record

ArticleeLife2021

Ssl2/TFIIH function in transcription start site scanning by RNA polymerase II in

Tingting Zhao, Irina O Vvedenskaya, William Km Lai, Shrabani Basu, B Franklin Pugh, Bryce E Nickels, Craig D Kaplan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Tingting ZhaoDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.
Irina O VvedenskayaDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, United States.
William Km LaiDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.
Shrabani BasuDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0001-5096-5490
B Franklin PughDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.ORCID 0000-0001-8341-4476
Bryce E NickelsDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, United States.ORCID 0000-0001-7449-8831
Craig D KaplanDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0002-7518-695X
University of Pittsburgh · USCornell University · USRutgers, The State University of New Jersey · US

Funding

Transcription: Mechanism and RegulationR35GM118059 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI NICKELS, BRYCE EDWARD · 2016 to 2025
$7.1M
REGULATION OF TBP DIMERSR01GM059055 · NIGMS · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI PUGH, B FRANKLIN · 2000 to 2020
$6.6M
Mechanism and Regulation of RNA Polymerase II ElongationR01GM097260 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, CRAIG · 2011 to 2020
$3.3M
"Mechanisms of RNA Polymerase II initiation"R01GM120450 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, CRAIG · 2016 to 2019
$1.7M
NIGMS NIH HHS R01 GM059055NIGMS NIH HHS R01 GM097260NIGMS NIH HHS R01 GM120450NIGMS NIH HHS R35 GM118059
6 · The paper itself

Abstract

In

Indexed as

Transcription Initiation, GeneticTranscription Initiation SiteDNA HelicasesRNA Polymerase IISaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Factor TFIIHDNA HelicasesRNA Polymerase IISaccharomyces cerevisiae ProteinsSSL2 protein, S cerevisiaeTranscription Factor TFIIHgeneral transcription factorsgeneticsgenomicsRNA polymerase IIS. cerevisiaetranscription initiationtranscription start siteyeast

Identifiers

PMID34652274
PMCPMC8589449
OpenAlexW3205776142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.