Evidence map›Paper›PMID 34652130›Full record

ArticleACS synthetic biology2021

Emergent Biological Endurance Depends on Extracellular Matrix Composition of Three-Dimensionally Printed

Srikkanth Balasubramanian, Kui Yu, Diana Vasquez Cardenas, Marie-Eve Aubin-Tam, Anne S Meyer

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Reproducible 3D bioprinting ofMicrobiology spectrum · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Probing the growth and mechanical properties ofSynthetic and systems biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Srikkanth BalasubramanianDepartment of Sustainable Design Engineering, Faculty of Industrial Design Engineering, Delft University of Technology, 2628 CE Delft, The Netherlands.
Kui YuDepartment of Bionanoscience & Kavli Institute of Nanoscience, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Diana Vasquez CardenasDepartment of Biotechnology, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Marie-Eve Aubin-TamDepartment of Bionanoscience & Kavli Institute of Nanoscience, Delft University of Technology, 2629 HZ Delft, The Netherlands.ORCID 0000-0001-9995-2623
Anne S MeyerDepartment of Biology, University of Rochester, Rochester, New York 14627, United States.ORCID 0000-0002-4164-0122
Delft University of Technology · NLUniversity of Rochester · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms are three-dimensional (3D) bacterial communities that exhibit a highly self-organized nature in terms of their composition and complex architecture. Bacteria in biofilms display emergent biological properties, such as resistance to antimicrobials and disinfectants that the individual planktonic cells lack. Bacterial biofilms possess specialized architectural features including unique extracellular matrix compositions and a distinct spatially patterned arrangement of cells and matrix components within the biofilm. It is unclear which of these architectural elements of bacterial biofilms lead to the development of their emergent biological properties. Here, we report a 3D printing-based technique for studying the emergent resistance behaviors of

Indexed as

Bacterial ProteinsBiofilmsCelluloseEscherichia coliExtracellular MatrixPrinting, Three-DimensionalBacterial ProteinsCellulose3D bioprintingbiofilmscellulosecurli fibersdisinfectant resistancesynthetic biology

Identifiers

PMID34652130
PMCPMC8609572
OpenAlexW3205183215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.