Evidence map›Paper›PMID 34651241›Full record

ArticleClinical & experimental metastasis2021

Stereotactic body radiation therapy for adrenal gland metastases: outcome and predictive factors from a multicenter analysis.

Ciro Franzese, Luca Nicosia, Giuseppe Facondo, Lorenzo Lo Faro, Francesco Cuccia, Gianluca Vullo, Mattia Falchetto Osti, Filippo Alongi, Marta Scorsetti

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical & experimental metastasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ciro FranzeseDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Pieve Emanuele, Milan, Italy.
Luca NicosiaAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Cancer Care Center, via Don Sempreboni 5, 37034, Verona, Negrar, Italy. lucanicosia.rg@gmail.com.ORCID 0000-0002-0731-8041
Giuseppe FacondoDepartment of Radiation Oncology, Sant'Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
Lorenzo Lo FaroDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Pieve Emanuele, Milan, Italy.
Francesco CucciaAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Cancer Care Center, via Don Sempreboni 5, 37034, Verona, Negrar, Italy.
Gianluca VulloDepartment of Radiation Oncology, Sant'Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
Mattia Falchetto OstiDepartment of Radiation Oncology, Sant'Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
Filippo AlongiAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Cancer Care Center, via Don Sempreboni 5, 37034, Verona, Negrar, Italy.
Marta ScorsettiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Pieve Emanuele, Milan, Italy.
Humanitas University · ITOspedale Sacro Cuore Don Calabria · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenal metastases occur in 15-35% of oncological patients. Surgery is the first treatment option. Stereotactic body radiotherapy (SBRT) has been largely explored in oligometastatic patients unfit for surgery, representing an effective and non-invasive local treatment. The results of a multi-institutional experience of SBRT on adrenal metastases in the oligorecurrent or oligoprogressive setting are herein reported. We collected data of adrenal gland metastases treated with SBRT in three Italian centers from 2010 to 2020. End-points of the present study were: Overall survival (OS), Local control of treated metastases (LC), Progression free survival (PFS), and toxicity. 149 adrenal gland metastases were treated with SBRT in 142 patients. The most common primary tumor was lung cancer (58.4%), followed by kidney cancer (9.4%). Median lesion's volume was 28.5 cm

Indexed as

MetastasectomyRadiosurgeryAdrenal Gland NeoplasmsAdultAgedAged, 80 and overClinical Decision-MakingDisease-Free SurvivalDisease ProgressionFemaleHumansItalyMaleMiddle AgedPatient SelectionRadiotherapy DosageAdrenal glandOligometastasesOligometastaticSABRSBRTStereotactic radiation therapy

Identifiers

PMID34651241
OpenAlexW3205715601

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.