Evidence map›Paper›PMID 34651209›Full record

ArticleAnalytical and bioanalytical chemistry2022

A double-spike MC TIMS measurement procedure for low-amount Ca isotopic analysis of limited biological tissue samples.

A Retzmann, D Walls, K A Miller, J Irrgeher, T Prohaska, M E Wieser

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Low-levelAnalytical and bioanalytical chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A RetzmannDepartment General, Analytical and Physical Chemistry, Chair of General and Analytical Chemistry, Montanuniversität Leoben, Leoben, Austria.
D WallsDepartment of Physics and Astronomy, University of Calgary, Calgary, Canada.
K A MillerDepartment of Physics and Astronomy, University of Calgary, Calgary, Canada.
J IrrgeherDepartment General, Analytical and Physical Chemistry, Chair of General and Analytical Chemistry, Montanuniversität Leoben, Leoben, Austria.
T ProhaskaDepartment General, Analytical and Physical Chemistry, Chair of General and Analytical Chemistry, Montanuniversität Leoben, Leoben, Austria.
M E WieserDepartment of Physics and Astronomy, University of Calgary, Calgary, Canada. mwieser@ucalgary.ca.

Funding

Austrian Academy of Sciences Chemical Monthly fellowship (2018)Natural Sciences and Engineering Research Council of Canada Discovery Research GrantUniversity of Calgary Faculty of Science Grand Challenges Fund
6 · The paper itself

Abstract

The application of Ca isotopic analysis in biomedical studies has great potential to identify changes in Ca metabolism and bone metabolism. Reliable measurement of Ca isotope-amount ratios is challenging considering limited Ca amounts and significant procedural blank levels. In this study, Ca purification was performed using the DGA Resin, optimized for low procedural blanks and separation of Ca from matrix elements and isobaric interferences (Na, Mg, K, Ti, Fe, Ba), while maintaining quasi-quantitative recoveries which are sufficient since a

Indexed as

Chemical FractionationIsotopesHairHumansMass SpectrometryIsotopesDGA ResinDouble-spikeHair CRMsTIMSδ(44Ca/40Ca)δ(44Ca/42Ca)

Identifiers

PMID34651209

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.