Evidence map›Paper›PMID 34651146›Full record

ArticleProceedings of the ... IAPR International Conference on Pattern Recognition. International Conference on Pattern Recognition2021

Multi-focus Image Fusion for Confocal Microscopy Using U-Net Regression Map.

Maruf Hossain Shuvo, Yasmin M Kassim, Filiz Bunyak, Olga V Glinskii, Leike Xie, Vladislav V Glinsky, Virginia H Huxley, Mahesh M Thakkar, Kannappan Palaniappan

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the ... IAPR International Conference on Pattern Recognition. International Conference on Pattern Recognition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Ensemble of Deep Learning Cascades for Segmentation of Blood Vessels in Confocal Microscopy Images.IEEE Applied Imagery Pattern Recognition Workshop : [proceedings]. IEEE Applied Imagery Pattern Recognition Workshop · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Maruf Hossain ShuvoComputational Imaging and VisAnalysis (CIVA) Lab, Department of Electrical Engineering and Computer Science, University of Missouri-Columbia, MO 65211 USA.
Yasmin M KassimComputational Imaging and VisAnalysis (CIVA) Lab, Department of Electrical Engineering and Computer Science, University of Missouri-Columbia, MO 65211 USA.
Filiz BunyakComputational Imaging and VisAnalysis (CIVA) Lab, Department of Electrical Engineering and Computer Science, University of Missouri-Columbia, MO 65211 USA.
Olga V GlinskiiDepartment of Medical Pharmacology and Physiology, University of Missouri-Columbia, MO 65211 USA.
Leike XieNational Center for Gender Physiology, Dalton Cardiovascular Research Center, University of Missouri-Columbia, MO 65211 USA.
Vladislav V GlinskyDepartment of Pathology and Anatomical Sciences, University of Missouri-Columbia, MO 65211 USA.
Virginia H HuxleyDepartment of Medical Pharmacology and Physiology, University of Missouri-Columbia, MO 65211 USA.
Mahesh M ThakkarDepartment of Neurology, University of Missouri-Columbia, MO 65211 USA.
Kannappan PalaniappanComputational Imaging and VisAnalysis (CIVA) Lab, Department of Electrical Engineering and Computer Science, University of Missouri-Columbia, MO 65211 USA.
Cardiovascular Research Center · BRUniversity of Missouri · US

Funding

Quantitative analysis of estrogen and sleep deprivation-induced blood and lymphatic vascular remodeling in the brain systemR01NS110915 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI GLINSKII, OLGA V, PALANIAPPAN, KANNAPPAN · 2019 to 2023
$2.7M
Insulin as a Regulator of Microvascular ExchangeR01DK095501 · NIDDK · UNIVERSITY OF MISSOURI-COLUMBIA · PI HUXLEY, VIRGINIA H · 2013 to 2016
$1.5M
NIDDK NIH HHS R01 DK095501NINDS NIH HHS R01 NS110915
6 · The paper itself

Abstract

Characterizing the spatial relationship between blood vessel and lymphatic vascular structures, in the mice dura mater tissue, is useful for modeling fluid flows and changes in dynamics in various disease processes. We propose a new deep learning-based approach to fuse a set of multi-channel single-focus microscopy images within each volumetric z-stack into a single fused image that accurately captures as much of the vascular structures as possible. The red spectral channel captures small blood vessels and the green fluorescence channel images lymphatics structures in the intact dura mater attached to bone. The deep architecture Multi-Channel Fusion U-Net (MCFU-Net) combines multi-slice regression likelihood maps of thin linear structures using max pooling for each channel independently to estimate a slice-based focus selection map. We compare MCFU-Net with a widely used derivative-based multi-scale Hessian fusion method [8]. The multi-scale Hessian-based fusion produces dark-halos, non-homogeneous backgrounds and less detailed anatomical structures. Perception based no-reference image quality assessment metrics PIQUE, NIQE, and BRISQUE confirm the effectiveness of the proposed method.

Indexed as

convolutional neural networkHessianlymphatics like structuresmulti-focus image fusionU-Net

Identifiers

PMID34651146
PMCPMC8513773
OpenAlexW3157026079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.