Evidence map›Paper›PMID 34651138›Full record

ArticleCritical care explorations2021

Allogeneic Hematopoietic Stem Cell Transplant Infusion During Venovenous Extracorporeal Membrane Oxygenation Support.

Rayan Qutob, Xinyu Ji, Nawaporn Assanangkornchai, Vladimir Sapon-Cousineau, May Tam, Rita Larotonda, Jean-Pierre Routy, Gizelle Popradi, Gordan Samoukovic

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Rayan QutobDepartment of Critical Care Medicine, McGill University, Montreal, QC, Canada.
Xinyu JiDepartment of Internal Medicine, Faculty of Medicine, McGill University, Montreal, QC, Canada.
Nawaporn AssanangkornchaiDepartment of Critical Care Medicine, McGill University, Montreal, QC, Canada.
Vladimir Sapon-CousineauDepartment of Hematology, McGill University, Montreal, QC, Canada.
May TamPerfusion Department, McGill University, Montreal, QC, Canada.
Rita LarotondaNursing Department, McGill University, Montreal, QC, Canada.
Jean-Pierre RoutyDepartment of Hematology, McGill University, Montreal, QC, Canada.
Gizelle PopradiDepartment of Hematology, McGill University, Montreal, QC, Canada.
Gordan SamoukovicDepartment of Critical Care Medicine, McGill University, Montreal, QC, Canada.
McGill University · CAPrince of Songkla University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of hematopoietic stem cell transplant complicated by respiratory failure has been facilitated by the use of extracorporeal membrane oxygenation as a bridge to curative chemotherapeutic options. This is the first report of hematopoietic stem cell transplantation on extracorporeal membrane oxygenation in the adult population. CASE SUMMARY: A 28-year-old woman diagnosed with idiopathic aplastic anemia complicated by acute respiratory distress syndrome secondary to pneumonia required venovenous extracorporeal membrane oxygenation to supplement oxygenation and ventilation. She received hematopoietic stem cell transplantation while she was on extracorporeal membrane oxygenation support. MAIN RESULTS AND

conclusionDelivery of the stem cell through extracorporeal membrane oxygenation circuit was successful in the described patient. There was no sequestered stem cell in extracorporeal membrane oxygenation circuit, and she was found to have 90% donor chimerism suggesting successful engraftment. This report showed that infusion of stem cell through extracorporeal membrane oxygenation circuit is safe and feasible, and our results suggest that successful engraftment is possible.

Indexed as

acute respiratory distress syndromeaplastic anemiaengraftmentextracorporeal life supportextracorporeal membrane oxygenationhematopoietic stem cell transplantation

Identifiers

PMID34651138
PMCPMC8505339
OpenAlexW3207238417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.