Evidence map›Paper›PMID 34651084›Full record

ArticleBMJ open ophthalmology2021

Long-term outcome of primary intraocular lens implantation in bilateral congenital cataract in infants with a median age of 35 days at surgery: a case series.

Mari Kathrine Sand, Symira Cholidis, Kjartan Rimstad, Elise Dees Krekling, Olav Kristianslund, Liv Drolsum

Open access · goldAbstract read
In one paragraph

Article in BMJ open ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Bag-in-the-lens technique.Frontiers in ophthalmology · 2026
    Review
  2. Risk factors for capsular phimosis following congenital cataract extraction.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mari Kathrine SandDepartment of Ophthalmology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-7454-3209
Symira CholidisDepartment of Ophthalmology, Oslo University Hospital, Oslo, Norway.
Kjartan RimstadIndependent Researcher, Oslo, Norway.
Elise Dees KreklingDepartment of Optometry, Radiography and Lighting Design, University of South-Eastern Norway (USN), Kongsberg, Norway.
Olav KristianslundDepartment of Ophthalmology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-3390-9811
Liv DrolsumDepartment of Ophthalmology, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOUniversity of South-Eastern Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the long-term visual outcome and safety after bilateral cataract surgery with primary intraocular lens (IOL) implantation in infants with visually significant cataract at birth operated before 12 weeks of age. METHODS AND ANALYSIS: Medical records of infants with congenital cataract who had bilateral surgery with primary IOL implantation before 12 weeks of age at Oslo University Hospital between 2007 and 2016 were retrospectively reviewed. Fifteen infants (30 eyes) were enrolled for a prospective study examination in 2017. Corrected distance visual acuity (CDVA) and intraocular pressure (IOP) were assessed. Visual axis opacification (VAO) was defined as opacification on the anterior or posterior surface of the IOL, capsular phimosis or fibrinous membrane. Secondary glaucoma was evaluated according to international guidelines.

resultsMedian age at the time of primary surgery was 35 days (range, 15 to 70 days). There were no serious intraoperative complications, and all eyes had the IOL implanted in the capsular bag. After a median follow-up of 6.1 years (range, 1.5 to 10.2 years), the CDVA was 0.5 logMAR (range, 1.2 to 0.04). All eyes had surgery for VAO and the median number of surgical procedures was 2.0 (range, 1 to 5). The cumulative incidence of secondary glaucoma was 10% after 5 years of follow-up.

conclusionPrimary IOL implantation before 12 weeks of age gave a satisfactory visual outcome, and the incidence of secondary glaucoma was similar to that reported after primary IOL implantation in older infants. However, the risk of VAO was high.

Indexed as

anterior chamberchild health (paediatrics)lens and zonulesvision

Identifiers

PMID34651084
PMCPMC8487206
OpenAlexW3202495559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.