Evidence map›Paper›PMID 34651052›Full record

ArticleOpen forum infectious diseases2021

Low Diversity in Nasal Microbiome Associated With

Ni Zhao, Dina F Khamash, Hyunwook Koh, Annie Voskertchian, Emily Egbert, Emmanuel F Mongodin, James R White, Lauren Hittle, Elizabeth Colantuoni, Aaron M Milstone

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Computational and in vitro evaluation of probiotic treatments for nasalProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Frontiers in microbiology · 2025
    Article
  6. Article
  7. Article
  8. Frontiers in microbiomes · 2024
    Article
  9. Microbiome dysbiosis: a modifiable state and target to prevent Staphylococcus aureus infections and other diseases in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ni ZhaoDepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-7762-3949
Dina F KhamashDivision of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hyunwook KohDeptartment of Applied Mathematics & Statistics, The State University of New York, Korea (SUNY Korea), Incheon, South Korea.
Annie VoskertchianDivision of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Emily EgbertDivision of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Emmanuel F MongodinInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
James R WhiteResphera Biosciences, Baltimore, Maryland, USA.
Lauren HittleResphera Biosciences, Baltimore, Maryland, USA.
Elizabeth ColantuoniDepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Aaron M MilstoneDivision of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Johns Hopkins University · USResphera Biosciences · USSUNY Korea · KRUniversity of Maryland, Baltimore · US

Funding

Mentoring in prevention of hospital-acquired infections and antibiotic resistanceK24AI141580 · NIAID · JOHNS HOPKINS UNIVERSITY · PI AARON M MILSTONE · 2019 to 2026
$1.4M
Association of the evolving nasal microbiome and neonatal acquisition of Staphylococcus aureus colonizationR21AI135179 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MILSTONE, AARON M · 2018 to 2019
$459k
AHRQ HHS R01 HS022872NCEZID CDC HHS U54 CK000617NIAID NIH HHS K24 AI141580NIAID NIH HHS R21 AI135179
6 · The paper itself

Abstract

background

methodsWe performed 2 matched case-control studies (colonization cohort-neonates who did and did not acquire

resultsIn the colonization cohort, 43

conclusionsThe association of increased

Indexed as

bloodstream infectionmicrobiomeneonatesStaphylococcus aureus

Identifiers

PMID34651052
PMCPMC8507450
OpenAlexW3200078456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.