Evidence map›Paper›PMID 34650981›Full record

ArticleFrontiers in cell and developmental biology2021

Advanced Flow Cytometry Analysis Algorithms for Optimizing the Detection of "Different From Normal" Immunophenotypes in Acute Myeloid Blasts.

Carmen-Mariana Aanei, Richard Veyrat-Masson, Lauren Rigollet, Jérémie Stagnara, Emmanuelle Tavernier Tardy, Elisabeth Daguenet, Denis Guyotat, Lydia Campos Catafal

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. DOGMA-seq and multimodal, single-cell analysis in acute myeloid leukemia.International review of cell and molecular biology · 2025
    Review
  6. Article
  7. Review
  8. MRD-directed and risk-adapted individualized stratified treatment of AML.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Carmen-Mariana AaneiLaboratoire d'Hématologie, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.
Richard Veyrat-MassonLaboratoire d'Hématologie, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
Lauren RigolletLaboratoire d'Hématologie, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.
Jérémie StagnaraLaboratoire d'Hématologie, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.
Emmanuelle Tavernier TardyInstitut de Cancérologie Lucien Neuwirth, Saint-Priest-en-Jarez, France.
Elisabeth DaguenetInstitut de Cancérologie Lucien Neuwirth, Saint-Priest-en-Jarez, France.
Denis GuyotatInstitut de Cancérologie Lucien Neuwirth, Saint-Priest-en-Jarez, France.
Lydia Campos CatafalLaboratoire d'Hématologie, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.
Centre Hospitalier Universitaire de Saint-Étienne · FRInstitute Cancer De La Loire Lucien Neuwirth · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemias (AMLs) are a group of hematologic malignancies that are heterogeneous in their molecular and immunophenotypic profiles. Identification of the immunophenotypic differences between AML blasts and normal myeloid hematopoietic precursors (myHPCs) is a prerequisite to achieving better performance in AML measurable residual disease follow-ups. In the present study, we applied high-dimensional analysis algorithms provided by the Infinicyt 2.0 and Cytobank software to evaluate the efficacy of antibody combinations of the EuroFlow AML/myelodysplastic syndrome panel to distinguish AML blasts with recurrent genetic abnormalities (

Indexed as

AML with recurrent genetic abnormalitiesCitrusdifferent-from-normal (DfN)InfinicytSPADEviSNE

Identifiers

PMID34650981
PMCPMC8506133
OpenAlexW3203286977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.