Evidence map›Paper›PMID 34650819›Full record

ArticleCase reports in critical care2021

CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm.

Alice-Christin Acevedo, Michael Zoller, Christina Scharf, Uwe Liebchen, Michael Irlbeck, Ines Schroeder

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alice-Christin AcevedoDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.ORCID https://orcid.org/0000-0002-3164-9203
Michael ZollerDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
Christina ScharfDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
Uwe LiebchenDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
Michael IrlbeckDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
Ines SchroederDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. Recent publications addressing therapy of cytokine storms recommended new extracorporeal therapies such as hemoadsorption. This case report describes a 59-year-old SARS-CoV-2-positive patient with severe ARDS. Due to severe hyperinflammation with concomitant hemodynamic instability and progressive renal failure, combination of continuous renal replacement and CytoSorb® hemoadsorption therapy was initiated. Treatment resulted immediately in a control of the hyperinflammatory response. Simultaneously, lung function continued to improve accompanied by profound hemodynamic stabilization. We report the successful utilization of CytoSorb® hemoadsorption in the treatment of a patient with SARS-CoV-2-induced cytokine storm syndrome.

Identifiers

PMID34650819
PMCPMC8510828
OpenAlexW3206283548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.