Evidence map›Paper›PMID 34650760›Full record

ArticleAmerican journal of translational research2021

Clinical efficacy of tanshinone capsules combined with varying concentrations of 5-ALA-PDT in the treatment of cystic acne.

Yan Yao, Jing Zuo, Li Chen

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yan YaoDepartment of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing 210029, Jiangsu Province, China.
Jing ZuoDepartment of Ophthalmology, Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing 210029, Jiangsu Province, China.
Li ChenDepartment of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing 210029, Jiangsu Province, China.
Nanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the clinical effectiveness and safety of tanshinone capsules combined with varying concentrations of 5-aminoketovaleric acid photodynamic therapy (5-ALA-PDT) in the treatment of cystic acne.

methodsA total of 97 patients with cystic acne treated in our hospital were enrolled in the study and divided into group A (n = 34, tanshinone capsules combined with 5% 5-ALA-PDT), group B (n = 31, tanshinone capsules combined with 7.5% 5-ALA-PDT), and group C (n = 32, tanshinone capsules combined with 10% 5-ALA-PDT). The number of skin lesions, the global acne grading system (GAGS) scores, the clinical effectiveness, the adverse reactions, and the recurrence rates were compared among the three groups.

resultsThe number of skin lesions and the GAGS scores were lower in all three groups at two weeks, one month, and three months of treatment (

conclusionsTanshinone capsules combined with 7.5% 5-ALA-PDT showed the optimal clinical effectiveness and safety in the treatment of cystic acne.

Indexed as

5-aminoketovaleric acid photodynamic therapyclinical effectivenesssafetyTanshinone capsules

Identifiers

PMID34650760
PMCPMC8507074
OpenAlexW3205396546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.