ArticleAmerican journal of translational research2021
The application of Gensini score and IL-1ra in assessing the condition and prognosis of patients with coronary artery disease.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Systematic review and meta - analysis of risk prediction models for heart failure after PCI in patients with acute myocardial infarction.BMC cardiovascular disorders · 2026Pooled it
- Combined discriminative value of SII and sdLDL-C for 1-year major adverse cardiovascular events in patients with unstable angina pectoris.Frontiers in cardiovascular medicine · 2026Article
- Correlation between the neutrophil-to-lymphocyte ratio with the severity of new-onset coronary artery disease in various glucose metabolic states: a retrospective study.BMC cardiovascular disorders · 2025Article
- Risk analysis and risk prediction of in-hospital heart failure in patients with acute myocardial infarction after emergency intervention surgery.BMC cardiovascular disorders · 2024Article
- Screening significance of systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) in coronary heart disease of symptomatic youth.Immunity, inflammation and disease · 2024Article
- [Correlation of serum ferredoxin 1 and lipoic acid levels with severity of coronary artery disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Analyzing the non-linear relationship between fasting blood glucose levels and Gensini score in patients with STEMI.Frontiers in cardiovascular medicine · 2024Article
- Association between endothelin-1, nitric oxide, and Gensini score in chronic coronary syndrome.BMC cardiovascular disorders · 2023Article
- The potential relationship of coronary artery disease and hyperuricemia: A cardiometabolic risk factor.Heliyon · 2023Review
- Association Between Major Adverse Cardiovascular Events and the Gensini Score or Coronary Artery Calcification Score in Hypertensive Patients Who Have Undergone Coronary Computed Tomography Angiography.Cardiology research · 2023Article
- Relationship of the Circulating Endothelial Progenitor Cells to the Severity of a Coronary Artery Lesion in Unstable Angina.Cardiology research and practice · 2022Article
- 4'-phosphopantetheine acts as a potential antioxidant to limit atherosclerotic plaque formation by inhibiting ROS generation.Frontiers in physiology · 2022Article
- Correlation of TET-2 Levels with Disease Evaluation in AMI Patients.Contrast media & molecular imaging · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to investigate the value of Gensini score and interleukin-1 receptor antagonist (IL-1ra) in assessing the condition and prognosis of patients with coronary heart disease (CHD).
methodsAccording to their condition, 175 patients were divided into stable angina group (SA, 60 cases), unstable angina group (UA, 60 cases) and acute myocardial infarction group (AMI, 55 cases). The Gensini score, GRACE score, IL-1ra and troponin (Tn) were compared in the three groups. The correlation between Gensini score and GRACE score, IL-1ra and Tn, were explored. The patients were divided into death group (21 cases), adverse cardiovascular events group (MACE, 50 cases) and good prognosis group (104 cases) according to clinical outcomes. The ROC curve with regard to Gensini score, IL-1ra and the clinical outcome was plotted.
resultsWith the exacerbation of the disease, the Gensini score, GRACE score, IL-1ra and Tn were significantly higher in patients with CHD (
conclusionGensini score and IL-1ra reflect better the severity of CHD in patients with CHD, and also the AUC of 0.9350 and 0.9499 (P<0.001). It can be used in the prognostic evaluation of patients with CHD.
Indexed as
Identifiers
34650711PMC8506997W3205745580What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.