Evidence map›Paper›PMID 34650696›Full record

ArticleAmerican journal of translational research2021

Upregulation of the P2X7 receptor promotes Ca

Lin Shen, Zhengxin Wang, Rudan Wang, Xiaoyan Chen, Saiyu Cheng

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lin ShenDepartment of Neurology, The Second Affiliated Hospital of Army Medical University Chongqing 400037, China.
Zhengxin WangDepartment of Neurology and Neurosurgery, The Third Affiliated Hospital of Chongqing Medical University Chongqing 401120, China.
Rudan WangDepartment of Neurology, The Second Affiliated Hospital of Army Medical University Chongqing 400037, China.
Xiaoyan ChenDepartment of Neurology, The Second Affiliated Hospital of Army Medical University Chongqing 400037, China.
Saiyu ChengDepartment of Neurology and Neurosurgery, The Third Affiliated Hospital of Chongqing Medical University Chongqing 401120, China.
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation is a critical process in post-stroke depression (PSD). The ionotropic P2X7 receptor (P2X7R) functions as an ATP-gated nonselective ion channel permeable to Ca

Indexed as

Ca2+neuroinflammationP2X7 receptorpost-stroke depression

Identifiers

PMID34650696
PMCPMC8507060
OpenAlexW3205788903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.