Evidence map›Paper›PMID 34650611›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Efficacy of Qingfei Paidu Decoction on Patients with COVID-19 Pneumonia in Wuhan, China: A Propensity Score Matching Study.

Zhen Liu, Shan Du, Fei Shao, Haibin Li, Shuang Xu, Xuedi Ma, Zhouming Xu, Hao Cui, Changxiao Yu, Yang Wu and 6 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A deep dive into herbal extraction: Techniques, trends, and technological advancements.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2026
    Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Zhen LiuDepartment of Emergency Medicine, Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing, China.
Shan DuDepartment of Neurology, Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing, China.
Fei ShaoDepartment of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Haibin LiDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.
Shuang XuDepartment of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xuedi MaAI Research Division, A.I. Phoenix Technology Co., Ltd., Hong Kong, China.
Zhouming XuAI Research Division, A.I. Phoenix Technology Co., Ltd., Hong Kong, China.
Hao CuiBeijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing, China.
Changxiao YuBeijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing, China.
Yang WuBeijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing, China.
Feng WangDepartment of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Liyan LiDepartment of Emergency Medicine, Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing, China.
Rui ChenDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China.
Hui QiuDepartment of Emergency Surgery, the West Campus of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ziren TangDepartment of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Peng SunDepartment of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0001-9576-6102
Capital Medical University · CNIntegrated Chinese Medicine (China) · CNUnion Hospital · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn view of the global efforts to develop effective treatments for the current worldwide coronavirus 2019 (COVID-19) pandemic, Qingfei Paidu decoction (QPD), a novel traditional Chinese medicine (TCM) prescription, was formulated as an optimized combination of constituents of classic prescriptions used to treat numerous febrile and respiratory-related diseases. This prescription has been used to treat patients with COVID-19 pneumonia in Wuhan, China.

methodsIn this single-center, retrospective, observational study, we identified eligible participants who received a laboratory diagnosis of COVID-19 between January 15 and March 15, 2020, in the west campus of Union Hospital in Wuhan, China. QPD was supplied as an oral liquid packaged in 200-mL containers, and patients were orally administered one package twice daily 40 minutes after a meal. The primary outcome was death, which was compared between patients who did and did not receive QPD (QPD and NoQPD groups, respectively). Propensity score matching (PSM) was used to identify cohorts.

resultsIn total, 239 and 522 participants were enrolled in the QPD and NoQPD groups, respectively. After PSM at a 1 : 1 ratio, 446 patients meeting the criteria were included in the analysis with 223 in each arm. In the QPD and NoQPD groups, 7 (3.2%) and 29 (13.0%) patients died, and those in the QPD group had a significantly lower risk of death (hazard ratio (HR) 0.29, 95% CI: 0.13-0.67) than those in the NoQPD group (

conclusionThe use of QPD may reduce the risk of death in patients with COVID-19 pneumonia.

Identifiers

PMID34650611
PMCPMC8510827
OpenAlexW3202990910

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.