Evidence map›Paper›PMID 34650564›Full record

ArticleFrontiers in immunology2021

Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.

Bi-Ying Jin, Zhen Li, Ya-Nan Xia, Li-Xiang Li, Zi-Xiao Zhao, Xiao-Yu Li, Yan Li, Bing Li, Ru-Chen Zhou, Shi-Chen Fu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  10. iScience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Bi-Ying JinDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Zhen LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Ya-Nan XiaDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Li-Xiang LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Zi-Xiao ZhaoDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Xiao-Yu LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Yan LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Bing LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Ru-Chen ZhouDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Shi-Chen FuDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Shi-Yang LiAdvanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yan-Qing LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
Qilu Hospital of Shandong University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delivery by cesarean section (CS) is linked to an increased incidence of food allergies in children and affects early gut microbiota colonization. Furthermore, emerging evidence has connected disordered intestinal microbiota to food allergies. Here, we investigated the impact of CS on a rat model for food allergy to ovalbumin (OVA). Rats delivered by CS were found to be more responsive to OVA sensitization than vaginally born ones, displaying a greater reduction in rectal temperature upon challenge, worse diarrhea, and higher levels of OVA-specific antibodies and histamine. 16S rRNA sequencing of feces revealed reduced levels of

Indexed as

AllergensAnimalsBifidobacteriumCells, CulturedCesarean SectionDisease Models, AnimalDysbiosisFemaleFood HypersensitivityGastrointestinal MicrobiomeHumansImmunoglobulin ELactobacillusMaleOvalbuminPregnancyAllergensImmunoglobulin EOvalbuminRNA, Ribosomal, 16Scesarean sectionfood allergyintestinal microbiotaprobioticsTh2 responsetight junction

Identifiers

PMID34650564
PMCPMC8505808
OpenAlexW3204846287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.