ArticleFrontiers in microbiology2021
Low Concentrations of Chlorhexidine Inhibit the Formation and Structural Integrity of Enzyme-Treated Multispecies Oral Biofilms.
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Evaluation of the alkaline water effect on the salivary bacteria of children: preliminary randomized trial.Scientific reports · 2026Trial
- Revisiting the ocular use of chlorhexidine: an agent to remember in multidrug-resistant bacterial and fungal keratitis.International ophthalmology · 2026Review
- Targeting Oral Biofilms: Comparative In Vitro Evaluation of Commercial Dental Antiseptics Against Clinical and Reference Microbial Strains.International journal of molecular sciences · 2026Article
- Polymeric Sustained-Release Chlorhexidine Coating on Gutta-Percha Points for Prolonged Intracanal Antimicrobial Delivery: An In Vitro Study.Pharmaceutics · 2026Article
- Chlorhexidine 0.02% treatment for refractory blepharoconjunctivitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Combined effects of nitrate and antimicrobial compounds on in vitro subgingival biofilms.Scientific reports · 2026Article
- Article
- PMA-qPCR to quantify viable cells in multispecies oral biofilm after disinfectant treatments.Biofilm · 2025Article
- Effect of Xylitol and Maltitol Chewing Gums on Plaque Reduction and Salivary pH Modulation: A Retrospective Study in Pediatric Patients.Dentistry journal · 2025Article
- Mechanistic Insight into the Anti-Bacterial/Anti-Biofilm Effects of Low Chlorhexidine Concentrations onMicroorganisms · 2024Article
- Microbial Dynamics in Periodontal Regeneration: Understanding Microbiome Shifts and the Role of Antifouling and Bactericidal Materials: A Narrative Review.Current issues in molecular biology · 2024Review
- High-Resolution Large-Area Image Analysis Deciphers the Distribution of Salmonella Cells and ECM Components in Biofilms Formed on Charged PEDOT:PSS Surfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Antibiofilm Effects of Oleuropein againstFoods (Basel, Switzerland) · 2023Article
- Article
- 3D Porous Collagen Matrices-A Reservoir for In Vitro Simultaneous Release of Tannic Acid and Chlorhexidine.Pharmaceutics · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The self-produced matrix of biofilms, consisting of extracellular polymeric substances, plays an important role in biofilm adhesion to surfaces and the structural integrity of biofilms. In dentistry, biofilms cause multiple diseases such as caries, periodontitis, and pulpitis. Disruption of these biofilms adhering to dental hard tissues may pose a major challenge since biofilms show higher tolerance to antimicrobials and antibiotics than planktonic cells. In this study, the effect of low concentrations of chlorhexidine (CHX) on enzyme-treated multispecies oral biofilm was investigated in an
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