Evidence map›Paper›PMID 34650454›Full record

ReviewFrontiers in psychiatry2021

Potential Cross-Links of Inflammation With Schizophreniform and Affective Symptoms: A Review and Outlook on Autoimmune Encephalitis and COVID-19.

Veronika Vasilevska, Paul C Guest, Konstantin Schlaaff, Enise I Incesoy, Harald Prüss, Johann Steiner

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Role of microRNA in Schizophrenia: A Scoping Review.International journal of molecular sciences · 2024
    Article
  4. The neurobiology of SARS-CoV-2 infection.Nature reviews. Neuroscience · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Veronika VasilevskaDepartment of Psychiatry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Paul C GuestLaboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, University of Campinas, Campinas, Brazil.
Konstantin SchlaaffDepartment of Psychiatry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Enise I IncesoyDepartment of Psychiatry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Harald PrüssGerman Center for Neurodegenerative Diseases, Berlin, Germany.
Johann SteinerDepartment of Psychiatry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Otto-von-Guericke University Magdeburg · DECharité - Universitätsmedizin Berlin · DEGerman Center for Neurodegenerative Diseases · DEUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on current implications of the SARS-CoV-2 pandemic with regards to mental health, we show that biological links exist between inflammation and mental illness in addition to psychoreactive effects. We describe key principles of the biological interaction of the immune system and the mind, as well as the possible routes of viral entry into the brain. In addition, we provide a stepwise scheme for the diagnosis and therapy of autoimmune-encephalitis with schizophrenia-like symptomatology as a general guide for clinical practice and in the specialized scenario of infections, such as those caused by the SARS-CoV-2 virus.

Indexed as

affective disorderautoimmune encephalitisinflammationneurological symptomsSARS-CoV-2schizophreniform disorder

Identifiers

PMID34650454
PMCPMC8507462
OpenAlexW3198954113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.