Evidence map›Paper›PMID 34650393›Full record

ArticleFood & nutrition research2021

Recombinant CRAMP-producing

Jiahong Li, Shiwen Yu, Xiaohua Pan, Ming Zhang, Zhuwu Lv, Li-Long Pan, Jia Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food & nutrition research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jiahong LiState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, P. R. China.
Shiwen YuDepartment of Obstetrics, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, P. R. China.
Xiaohua PanState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, P. R. China.
Ming ZhangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, P. R. China.
Zhuwu LvDepartment of Obstetrics, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, P. R. China.
Li-Long PanWuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, P. R. China.
Jia SunState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, P. R. China.
Jiangnan University · CNNanjing Medical University · CNState Key Laboratory of Food Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel diseases (IBDs) are generally characterized by persistent abdominal pain and diarrhea caused by chronic inflammation in the intestine. Cathelicidins are antimicrobial peptides with pleiotropic roles in anti-infection, wound healing, and immune modulation. However, the sensitivity to the acidic environment and short half-life of cathelicidins limit their application in IBD treatment. Recombinant cathelicidin-related antimicrobial peptide (CRAMP)-producing

objectiveThe aim of this study was to develop recombinant CRAMP-producing

designWe constructed two strains of CRAMP-producing

resultsBoth CRAMP-producing

conclusionsTogether, our data suggested that CRAMP-secreting

Indexed as

colitisCRAMPLactococcus lactis NZ9000probioticsUsp45

Identifiers

PMID34650393
PMCPMC8494263
OpenAlexW3203111012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.