Evidence map›Paper›PMID 34650234›Full record

ArticleNature chemistry2021

Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers.

Serena Arnaboldi, Gerardo Salinas, Aleksandar Karajić, Patrick Garrigue, Tiziana Benincori, Giorgia Bonetti, Roberto Cirilli, Sabrina Bichon, Sébastien Gounel, Nicolas Mano and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Dynamics of Nanomotors Propelled by Enzyme Cascade Reactions.International journal of molecular sciences · 2024
    Article
  3. Wireless asymmetric umpolung electrosynthesis.Chemical communications (Cambridge, England) · 2024
    Article
  4. Article
  5. Article
  6. AC-Bipolar Electropolymerization of 3,4-Ethylenedioxythiophene in Ionic Liquids.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  7. Review
  8. Wireless electrochemical actuation of soft materials towards chiral stimuli.Chemical communications (Cambridge, England) · 2023
    Review
  9. Biocompatible micromotors for biosensing.Analytical and bioanalytical chemistry · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Serena Arnaboldi *Institut des Sciences Moléculaires, UMR 5255, University of Bordeaux, CNRS, Bordeaux INP, Pessac, France.ORCID http://orcid.org/0000-0002-1981-4659
Gerardo Salinas *Institut des Sciences Moléculaires, UMR 5255, University of Bordeaux, CNRS, Bordeaux INP, Pessac, France.
Aleksandar KarajićInstitut des Sciences Moléculaires, UMR 5255, University of Bordeaux, CNRS, Bordeaux INP, Pessac, France.ORCID http://orcid.org/0000-0003-4605-180X
Patrick GarrigueInstitut des Sciences Moléculaires, UMR 5255, University of Bordeaux, CNRS, Bordeaux INP, Pessac, France.
Tiziana BenincoriDipartimento di Scienza e Alta Tecnologia, Università degli Studi dell'Insubria, Como, Italy.
Giorgia BonettiDipartimento di Scienza e Alta Tecnologia, Università degli Studi dell'Insubria, Como, Italy.
Roberto CirilliCentro Nazionale per il Controllo e la Valutazione dei Farmaci, Istituto Superiore di Sanità, Roma, Italy.
Sabrina BichonCentre de Recherche Paul Pascal, CNRS UMR 5031, University of Bordeaux, Pessac, France.
Sébastien GounelCentre de Recherche Paul Pascal, CNRS UMR 5031, University of Bordeaux, Pessac, France.
Nicolas ManoCentre de Recherche Paul Pascal, CNRS UMR 5031, University of Bordeaux, Pessac, France.ORCID http://orcid.org/0000-0001-7084-9323
Alexander KuhnInstitut des Sciences Moléculaires, UMR 5255, University of Bordeaux, CNRS, Bordeaux INP, Pessac, France. kuhn@enscbp.fr.ORCID http://orcid.org/0000-0002-1962-4863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key approach for designing bioinspired machines is to transfer concepts from nature to man-made structures by integrating biomolecules into artificial mechanical systems. This strategy allows the conversion of molecular information into macroscopic action. Here, we describe the design and dynamic behaviour of hybrid bioelectrochemical swimmers that move spontaneously at the air-water interface. Their motion is governed by the diastereomeric interactions between immobilized enantiopure oligomers and the enantiomers of a chiral probe molecule present in solution. These dynamic bipolar systems are able to convert chiral information present at the molecular level into enantiospecific macroscopic trajectories. Depending on the enantiomer in solution, the swimmers will move clockwise or anticlockwise; the concept can also be used for the direct visualization of the degree of enantiomeric excess by analysing the curvature of the trajectories. Deciphering in such a straightforward way the enantiomeric ratio could be useful for biomedical applications, for the read-out of food quality or as a more general analogue of polarimetric measurements.

Indexed as

AnimalsCattleDihydroxyphenylalanineEnzymes, ImmobilizedEquipment DesignMotionOligopeptidesOxidoreductases Acting on CH-CH Group DonorsPolymersPyrrolesStereoisomerismTechnologyThiophenesbilirubin oxidaseDihydroxyphenylalanineEnzymes, ImmobilizedOligopeptidesOxidoreductases Acting on CH-CH Group DonorsPolymerspolypyrrolePyrrolesThiophenes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.