Evidence map›Paper›PMID 34650096›Full record

ArticleScientific reports2021

Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis.

Eva Román, Maria Poca, Gerard Amorós-Figueras, Javier Rosell-Ferrer, Cristina Gely, Juan C Nieto, Silvia Vidal, Eulàlia Urgell, Andreu Ferrero-Gregori, Edilmar Alvarado-Tapias and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Bioimpedance Analysis to Predict Clinical Outcomes of Liver Cirrhosis in a Prospective Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Quantitative Assessment of Body Composition in Cirrhosis.Diagnostics (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. The use of phase angle in patients with digestive and liver diseases.Reviews in endocrine & metabolic disorders · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Eva RománEscola Universitària d'Infermeria EUI-Sant Pau, Barcelona, Spain.
Maria PocaDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Mas Casanovas, 90, 08041, Barcelona, Spain.
Gerard Amorós-FiguerasDepartment of Cardiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Javier Rosell-FerrerDepartment of Electronic Engineering, Universitat Politècnica de Catalunya, Barcelona, Spain.
Cristina GelyResearch Institute IIB-Sant Pau, Barcelona, Spain.
Juan C NietoResearch Institute IIB-Sant Pau, Barcelona, Spain.
Silvia VidalDepartment of Immunology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Eulàlia UrgellDepartment of Biochemistry, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Andreu Ferrero-GregoriINCLIVA Health Research Institute, Valencia, Spain.
Edilmar Alvarado-TapiasDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Mas Casanovas, 90, 08041, Barcelona, Spain.
Berta CuyàsDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Mas Casanovas, 90, 08041, Barcelona, Spain.
Elvira HernándezEscola Universitària d'Infermeria EUI-Sant Pau, Barcelona, Spain.
Rosalia SantesmasesEscola Universitària d'Infermeria EUI-Sant Pau, Barcelona, Spain.
Carlos GuarnerDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Mas Casanovas, 90, 08041, Barcelona, Spain.
Àngels EscorsellDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Mas Casanovas, 90, 08041, Barcelona, Spain.
German SorianoDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Mas Casanovas, 90, 08041, Barcelona, Spain. gsoriano@santpau.cat.
Hospital de Sant Pau · ESInstituto de Salud Carlos III · ESUniversitat Autònoma de Barcelona · ESINCLIVA Health Research Institute · ESUniversitat Politècnica de Catalunya · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phase angle is a versatile measurement to assess body composition, frailty and prognosis in patients with chronic diseases. In cirrhosis, patients often present alterations in body composition that are related to adverse outcomes. The phase angle could be useful to evaluate prognosis in these patients, but data are scarce. The aim was to analyse the prognostic value of the phase angle to predict clinically relevant events such as hospitalisation, falls, and mortality in patients with cirrhosis. Outpatients with cirrhosis were consecutively included and the phase angle was determined by electrical bioimpedance. Patients were prospectively followed to determine the incidence of hospitalisations, falls, and mortality. One hundred patients were included. Patients with phase angle ≤ 4.6° (n = 31) showed a higher probability of hospitalisation (35% vs 11%, p = 0.003), falls (41% vs 11%, p = 0.001) and mortality (26% vs 3%, p = 0.001) at 2-year follow-up than patients with PA > 4.6° (n = 69). In the multivariable analysis, the phase angle and MELD-Na were independent predictive factors of hospitalisation and mortality. Phase angle was the only predictive factor for falls. In conclusion, the phase angle showed to be a predictive marker for hospitalisation, falls, and mortality in outpatients with cirrhosis.

Indexed as

Body CompositionElectric ImpedanceAccidental FallsAgedFemaleHospitalizationHumansLiver CirrhosisMaleMiddle AgedPredictive Value of TestsPrognosis

Identifiers

PMID34650096
PMCPMC8516941
OpenAlexW3205738077

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.