ArticleScientific reports2021
Novel scaffold based graphene oxide doped electrospun iota carrageenan/polyvinyl alcohol for wound healing and pathogen reduction: in-vitro and in-vivo study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 33 citations in OpenAlex.
- Marine-Derived Polysaccharide Nanofibers for Wound Healing: Mechanistic Rationale, Biofabrication Strategies, and Translational Barriers.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Carbon nanomaterials: Exploring new frontiers in wound healing therapy.Bioengineering & translational medicine · 2025Review
- The dual activity of CaONPs as a cancer treatment substance and at the same time resistance to harmful microbes.Scientific reports · 2023Article
- Fabrication of Antibacterial Sponge Microneedles for Sampling Skin Interstitial Fluid.Pharmaceutics · 2023Article
- An innovative model for conductivity of graphene-based system by networked nano-sheets, interphase and tunneling zone.Scientific reports · 2022Article
- Carrageenan-Based Compounds as Wound Healing Materials.International journal of molecular sciences · 2022Review
- Marine Biopolymers as Bioactive Functional Ingredients of Electrospun Nanofibrous Scaffolds for Biomedical Applications.Marine drugs · 2022Review
- Polyvinyl Alcohol/Polyaniline/Carboxylated Graphene Oxide Nanocomposites for Coating Protection of Cast Iron in Simulated Seawater.Polymers · 2022Article
- Sustainable Microbial and Heavy Metal Reduction in Water Purification Systems Based on PVA/IC Nanofiber Membrane Doped with PANI/GO.Polymers · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing is a complicated multicellular process that involves several kinds of cells including macrophages, fibroblasts, endothelial cells, keratinocytes and platelets that are leading to their differentiation towards an anti-inflammatory response for producing several chemokines, cytokine and growth factors. In this study, electrospun nanofiber scaffold named (MNS) is composed of polyvinyl alcohol (PVA)/iota carrageenan (IC) and doped with partially reduced graphene oxide (prGO) that is successfully synthesized for wound healing and skin repair. The fabricated MNS was tested in case of infection and un-infection with E. coli and Staphylococcus and in both of the presence and in the absence of yeast as a natural nutritional supplement. Numerous biochemical parameters including total protein, albumin, urea and LDH, and hematological parameters were evaluated. Results revealed that the MNS was proved to be effective on most of the measured parameters and had exhibited efficient antibacterial inhibition activity. Whereas it can be used as an effective antimicrobial agent in wound healing, however, histopathological findings confirmed that the MNS caused re-epithelialization and the presence of yeast induced hair follicles growth and subsequently it may be used to hide formed head wound scar.
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