Evidence map›Paper›PMID 34649968›Full record

ArticleCold Spring Harbor molecular case studies2021

Identification of a recurrent mosaic

Timothy E Green, Duncan MacGregor, Susan M Carden, Rebekah V Harris, Chelsee A Hewitt, Samuel F Berkovic, Anthony J Penington, Ingrid E Scheffer, Michael S Hildebrand

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Cancer in Multilineage Mosaic RASopathies due to Pathogenic Variants in HRAS or KRAS: A Systematic Review and Meta-analysis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Timothy E GreenEpilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.
Duncan MacGregorAnatomical Pathology, The Royal Children's Hospital, Parkville, Victoria, Australia 3052.
Susan M CardenDepartment of Ophthalmology, The Royal Children's Hospital, Parkville, Victoria, Australia 3052.
Rebekah V HarrisEpilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.
Chelsee A HewittDepartment of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia 3000.
Samuel F BerkovicEpilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.ORCID 0000-0003-4580-841X
Anthony J Penington *Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, Victoria, Australia 3052.
Ingrid E Scheffer *Epilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.ORCID 0000-0002-2311-2174
Michael S Hildebrand *Epilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.
Royal Children's Hospital · AUThe University of Melbourne · AUPeter MacCallum Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nevus sebaceous syndrome (NSS) is a rare, multisystem neurocutaneous disorder, characterized by a congenital nevus, and may include brain malformations such as hemimegalencephaly or focal cortical dysplasia, ocular, and skeletal features. It has been associated with several eponyms including Schimmelpenning and Jadassohn. The isolated skin lesion, nevus sebaceous, is associated with postzygotic variants in

Indexed as

NevusProto-Oncogene Proteins p21(ras)BrainHumansNeoplasm Recurrence, Localras ProteinsKRAS protein, humanProto-Oncogene Proteins p21(ras)ras Proteinsfocal seizures with impairment of consciousness or awarenessgeneralized tonic seizuresintellectual disabilitylinear nevus sebaceousmild

Identifiers

PMID34649968
PMCPMC8751419
OpenAlexW3205264784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.