Evidence map›Paper›PMID 34649948›Full record

ArticleInternational journal of spine surgery2021

Fusing to the Sacrum/Pelvis: Does the Risk of Reoperation in Thoracolumbar Fusions Depend on Upper Instrumented Vertebrae (UIV) Selection?

Uchechi Iweala, Jack Zhong, Caroline Varlotta, Roee Ber, Laviel Fernandez, Eaman Balouch, Yong Kim, Themistocles Protopsaltis, Aaron J Buckland

Open access · diamondAbstract read
In one paragraph

Article in International journal of spine surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Uchechi IwealaDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Jack ZhongDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Caroline VarlottaDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Roee BerDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Laviel FernandezDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Eaman BalouchDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Yong KimDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Themistocles ProtopsaltisDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
Aaron J BucklandDivision of Spine, Department of Orthopedic Surgery, New York University Langone Health, New York City, NY.
NYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is controversy as to whether fusions should have the upper instrumented vertebrae (UIV) end in the upper lumbar spine or cross the thoracolumbar junction. This study compares outcomes and reoperation rates for thoracolumbar fusions to the sacrum or pelvis with UIV in the lower thoracic versus lumbar spine to determine if there is an increased reoperation rate depending on UIV selection.

methodsA retrospective review of prospectively collected data was conducted from a single-center database on adult patients with degeneration and deformity who underwent primary and revision fusions with a caudal level of S1 or ilium between 2012 and 2018. Fusions were classified as anterior, posterior, or combination approach. Revision fusions included patients who had spinal surgery at another institution prior to their revision surgery at the center. Patients were categorized into 1 of 3 groups based on UIV: T9-T11, upper lumbar region (L1-L2), and lower lumbar region (L3-L5). Inclusion criteria were age 18 years or older and at least 1 year of clinical follow-up. Patients were excluded from analysis if they had tumors, infections, or less than 1 year of follow-up after the index procedure.

resultsThe reoperation rates for the UIV groups in the thoracic (28%) and upper lumbar (27%) spine were nearly equal in magnitude and were both significantly higher than the reoperation rate in the lower lumbar group (18%,

conclusionConstructs with UIV in the thoracic spine suffer from higher rates of proximal junctional kyphosis and pseudoarthrosis, whereas those with UIV in the upper lumbar spine have higher rates of adjacent segment disease. Given this tradeoff, there is no certain recommendation on what UIV will result in a lower reoperation rate in thoracolumbar fusion constructs to the sacrum or pelvis. Surgeons must evaluate patient characteristics and risks to make the optimal decision.

Identifiers

PMID34649948
PMCPMC8651193
OpenAlexW3205482835

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.