Evidence map›Paper›PMID 34649607›Full record

ArticleParasites & vectors2021

Changes in porcine nutrient transport physiology in response to Ascaris suum infection.

Sarina Koehler, Andrea Springer, Nicole Issel, Stefanie Klinger, Christina Strube, Gerhard Breves

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Parasites & vectors · 2026
    Article
  2. AdultCurrent research in parasitology & vector-borne diseases · 2026
    Article
  3. Article
  4. Comparative Analysis ofAnimals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sarina Koehler *Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Hanover, Germany.
Andrea Springer *Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Hanover, Germany.
Nicole IsselInstitute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Hanover, Germany.
Stefanie KlingerInstitute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Hanover, Germany.
Christina StrubeInstitute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Hanover, Germany.
Gerhard BrevesInstitute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Hanover, Germany. Gerhard.Breves.iR@tiho-hannover.de.
University of Veterinary Medicine Hannover, Foundation · DE

Funding

Deutsche Forschungsgemeinschaft BR 780/23-1Deutsche Forschungsgemeinschaft STR 1171/14-1
6 · The paper itself

Abstract

backgroundThe roundworm Ascaris suum is one of the parasites with the greatest economic impact on pig farming. In this context, lower weight gain is hypothesized to be due to decreased nutrient absorption. This study aims at characterizing the effects of A. suum infection on intestinal nutrient transport processes and potential molecular mechanisms.

methodsThree groups of six piglets each were infected orally (10,000 embryonated A. suum eggs) in a single dose ("single infection"). Another three groups were infected orally (1000 embryonated eggs) for 10 consecutive days ("trickle infection"). Animals were necropsied 21, 35 and 49 days post-infection (dpi). Three groups served as respective controls. The Ussing chamber technique was applied for the functional characterization of small intestinal tissues [short-circuit currents (I

resultsPeptide- and alanine-induced changes in I

conclusionsIn contrast to the current hypothesis, these results indicate that the nutrient deprivation induced by A. suum cannot be explained by transcriptional or expression changes alone and requires further studies.

Indexed as

AlanineAnimalsAscariasisAscaris suumBiological TransportCytokinesGlucoseIntestinesNutrientsPeptidesSwineSwine DiseasesAlanineCytokinesGlucoseNutrientsPeptidesAlanine transportAscariasisAscariosisDipeptide transportElectrophysiologyGlucose transportSmall intestineUssing chamber

Identifiers

PMID34649607
PMCPMC8515719
OpenAlexW3206867691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.